Pathogenic evaluation of a turkey coronavirus isolate (TCoV NC1743) in turkey poults for establishing a TCoV disease model.


Journal

Veterinary microbiology
ISSN: 1873-2542
Titre abrégé: Vet Microbiol
Pays: Netherlands
ID NLM: 7705469

Informations de publication

Date de publication:
Aug 2021
Historique:
received: 27 04 2021
accepted: 16 06 2021
pubmed: 2 7 2021
medline: 16 7 2021
entrez: 1 7 2021
Statut: ppublish

Résumé

Turkey coronavirus (TCoV) can cause a highly contagious enteric disease in turkeys with severe economic losses in the global turkey industry. To date, no commercial vaccines are available for control of the disease. In the present study, we isolated a field strain (NC1743) of TCoV and evaluated its pathogenicity in specific-pathogen-free (SPF) turkey poults to establish a TCoV disease model. The results showed that the TCoV NC1743 isolate was pathogenic to turkey poults with a minimal infectious dose at 10

Identifiants

pubmed: 34197977
pii: S0378-1135(21)00178-4
doi: 10.1016/j.vetmic.2021.109155
pii:
doi:

Substances chimiques

Antibodies, Viral 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

109155

Informations de copyright

Published by Elsevier B.V.

Auteurs

Kyung-Il Kang (KI)

Southeast Poultry Research Laboratory, US National Poultry Research Center, Agricultural Research Service, United States Department of Agriculture, Athens, GA, 30605, USA.

J Michael Day (JM)

Southeast Poultry Research Laboratory, US National Poultry Research Center, Agricultural Research Service, United States Department of Agriculture, Athens, GA, 30605, USA.

Fatma Eldemery (F)

Southeast Poultry Research Laboratory, US National Poultry Research Center, Agricultural Research Service, United States Department of Agriculture, Athens, GA, 30605, USA.

Qingzhong Yu (Q)

Southeast Poultry Research Laboratory, US National Poultry Research Center, Agricultural Research Service, United States Department of Agriculture, Athens, GA, 30605, USA. Electronic address: qingzhong.yu@usda.gov.

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Classifications MeSH