The Potential Role of Bacteriophages in the Treatment of Recalcitrant Chronic Rhinosinusitis.

bacteriophages chronic rhinosinusitis endolysins phage therapy phages recalcitrant refractory therapy-resistant

Journal

Antibiotics (Basel, Switzerland)
ISSN: 2079-6382
Titre abrégé: Antibiotics (Basel)
Pays: Switzerland
ID NLM: 101637404

Informations de publication

Date de publication:
05 Jun 2021
Historique:
received: 30 04 2021
revised: 26 05 2021
accepted: 02 06 2021
entrez: 2 7 2021
pubmed: 3 7 2021
medline: 3 7 2021
Statut: epublish

Résumé

Chronic rhinosinusitis is a common condition affecting 5-12% of the general population worldwide. In a limited number of cases, the disease is recalcitrant to medical and surgical interventions, causing a major impact on physical, social and emotional well-being and increasing pressure on healthcare systems. Biofilm formation and dysbiosis caused by

Identifiants

pubmed: 34198741
pii: antibiotics10060675
doi: 10.3390/antibiotics10060675
pmc: PMC8229554
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

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Auteurs

Saartje Uyttebroek (S)

Department of Otorhinolaryngology, UZ Leuven, 3000 Leuven, Belgium.
Department of Neurosciences, Experimental Otorhinolaryngology, Rhinology Research, KU Leuven, 3000 Leuven, Belgium.

Jolien Onsea (J)

Department of Trauma Surgery, UZ Leuven, 3000 Leuven, Belgium.
Department of Development and Regeneration, Locomotor and Neurological Disorders, KU Leuven, 3000 Leuven, Belgium.

Willem-Jan Metsemakers (WJ)

Department of Trauma Surgery, UZ Leuven, 3000 Leuven, Belgium.
Department of Development and Regeneration, Locomotor and Neurological Disorders, KU Leuven, 3000 Leuven, Belgium.

Lieven Dupont (L)

Department of Pneumology, UZ Leuven, 3000 Leuven, Belgium.
Department of Chronic Diseases and Metabolism, Respiratory Diseases and Thoracic Surgery, KU Leuven, 3000 Leuven, Belgium.

David Devolder (D)

Pharmacy Department, UZ Leuven, 3000 Leuven, Belgium.

Jeroen Wagemans (J)

Department of Biosystems, Laboratory of Gene Technology, KU Leuven, 3000 Leuven, Belgium.

Rob Lavigne (R)

Department of Biosystems, Laboratory of Gene Technology, KU Leuven, 3000 Leuven, Belgium.

Isabel Spriet (I)

Pharmacy Department, UZ Leuven, 3000 Leuven, Belgium.
Department of Pharmaceutical and Pharmacological Sciences, Clinical Pharmacology and Pharmacotherapy, KU Leuven, 3000 Leuven, Belgium.

Laura Van Gerven (L)

Department of Otorhinolaryngology, UZ Leuven, 3000 Leuven, Belgium.
Department of Neurosciences, Experimental Otorhinolaryngology, Rhinology Research, KU Leuven, 3000 Leuven, Belgium.
Department of Microbiology, Immunology and Transplantation, Allergy and Clinical Immunology Research Unit, KU Leuven, 3000 Leuven, Belgium.

Classifications MeSH