Vaccines in Gastrointestinal Malignancies: From Prevention to Treatment.
gastrointestinal cancer
vaccines
Journal
Vaccines
ISSN: 2076-393X
Titre abrégé: Vaccines (Basel)
Pays: Switzerland
ID NLM: 101629355
Informations de publication
Date de publication:
13 Jun 2021
13 Jun 2021
Historique:
received:
01
05
2021
revised:
05
06
2021
accepted:
09
06
2021
entrez:
2
7
2021
pubmed:
3
7
2021
medline:
3
7
2021
Statut:
epublish
Résumé
Gastrointestinal (GI) malignancies are some of the most common and devastating malignancies and include colorectal, gastric, esophageal, hepatocellular, and pancreatic carcinomas, among others. Five-year survival rates for many of these malignancies remain low. The majority presents at an advanced stage with limited treatment options and poor overall survival. Treatment is advancing but not at the same speed as other malignancies. Chemotherapy and radiation treatments are still only partially effective in GI malignancies and cause significant side effects. Thus, there is an urgent need for novel strategies in the treatment of GI malignancies. Recently, immunotherapy and checkpoint inhibitors have entered as potential new therapeutic options for patients, and thus, cancer vaccines may play a major role in the future of treatment for these malignancies. Further advances in understanding the interaction between the tumor and immune system have led to the development of novel agents, such as cancer vaccines.
Identifiants
pubmed: 34199248
pii: vaccines9060647
doi: 10.3390/vaccines9060647
pmc: PMC8231997
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Références
Front Immunol. 2019 Aug 08;10:1832
pubmed: 31440238
Nat Rev Cancer. 2009 Dec;9(12):874-85
pubmed: 19935676
BMC Cancer. 2010 May 17;10:209
pubmed: 20478057
Vaccine. 2016 Jan 20;34(4):413-423
pubmed: 26691569
Gastroenterol Hepatol (N Y). 2011 Aug;7(8):517-64
pubmed: 22298988
J Clin Oncol. 2000 Jan;18(1):148-57
pubmed: 10623705
Cancer Res. 2009 Dec 1;69(23):9012-9
pubmed: 19903852
Curr Opin Drug Discov Devel. 2007 Sep;10(5):523-32
pubmed: 17786850
Expert Opin Biol Ther. 2012 Aug;12(8):1043-58
pubmed: 22577875
Lancet Oncol. 2012 Jun;13(6):607-15
pubmed: 22575588
J Natl Cancer Inst. 1997 Feb 19;89(4):293-300
pubmed: 9048833
Gastroenterology. 2016 Sep;151(3):472-480.e1
pubmed: 27269245
Cancer Treat Rev. 2020 Aug;88:102030
pubmed: 32505807
Cancer. 2009 Aug 15;115(16):3670-9
pubmed: 19536890
J Clin Oncol. 2006 Jul 1;24(19):3089-94
pubmed: 16809734
J Clin Oncol. 2015 Sep 1;33(25):2780-8
pubmed: 26014293
Proc Natl Acad Sci U S A. 2008 Dec 23;105(51):20422-7
pubmed: 19088187
Ann Oncol. 2006 Jun;17(6):974-80
pubmed: 16600979
J Natl Cancer Inst. 1995 Jul 5;87(13):982-90
pubmed: 7629885
Int J Oncol. 2014 Mar;44(3):662-8
pubmed: 24398900
Clin Cancer Res. 2006 May 1;12(9):2817-25
pubmed: 16675576
J Immunother. 2007 Oct;30(7):762-72
pubmed: 17893568
Adv Immunol. 2012;114:177-201
pubmed: 22449782
Nat Rev Immunol. 2018 Mar;18(3):183-194
pubmed: 29279613
Mol Ther. 2011 Mar;19(3):620-6
pubmed: 21157437
N Engl J Med. 2011 Jun 2;364(22):2119-27
pubmed: 21631324
Adv Immunol. 2016;130:25-74
pubmed: 26922999
Br J Cancer. 2004 Apr 5;90(7):1334-42
pubmed: 15054451
J Cancer. 2017 Feb 25;8(5):761-773
pubmed: 28382138
Yonago Acta Med. 2017 Jun 26;60(2):101-105
pubmed: 28701892
Front Oncol. 2019 Jan 21;9:19
pubmed: 30719425
Immunity. 2020 Jan 14;52(1):17-35
pubmed: 31940268
Oncoimmunology. 2016 Jan 19;5(5):e1129483
pubmed: 27467945
J Clin Oncol. 2010 Mar 1;28(7):1099-105
pubmed: 20100959
Clin Exp Immunol. 2017 Jan;187(1):53-63
pubmed: 27690272
Gastroenterology. 2017 May;152(6):1395-1406.e10
pubmed: 28188748
Clin Exp Med. 2012 Sep;12(3):173-80
pubmed: 21932124
Adv Cancer Res. 2013;119:421-75
pubmed: 23870514
Vaccine. 2011 May 9;29(20):3646-54
pubmed: 21435405
BMC Cancer. 2018 Jul 20;18(1):752
pubmed: 30029640
J Clin Invest. 2019 Sep 3;129(9):3952-3962
pubmed: 31424423
J Hematol Oncol. 2017 Apr 7;10(1):82
pubmed: 28388966
Anticancer Res. 2014 Jun;34(6):2689-700
pubmed: 24922629
Cancer Immunol Immunother. 2008 Sep;57(9):1413-20
pubmed: 18297281
Cancer. 2006 May 1;106(9):1908-16
pubmed: 16568451
Clin Cancer Res. 2012 Jul 1;18(13):3686-96
pubmed: 22577059
World J Gastroenterol. 2018 Dec 28;24(48):5418-5432
pubmed: 30622371
Nat Rev Cancer. 2006 Mar;6(3):204-16
pubmed: 16498443
NPJ Vaccines. 2019 Feb 8;4:7
pubmed: 30774998
Oncol Lett. 2018 Apr;15(4):4241-4247
pubmed: 29541190
J Transl Med. 2014 Feb 24;12:55
pubmed: 24565030
Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5088-93
pubmed: 20194765
J Transl Med. 2014 Mar 10;12:63
pubmed: 24612787
Cancer Res. 1979 Apr;39(4):1353-60
pubmed: 217533
N Engl J Med. 1991 Oct 24;325(17):1205-9
pubmed: 1922207
N Engl J Med. 2010 Jul 29;363(5):411-22
pubmed: 20818862
Annu Rev Immunol. 2000;18:767-811
pubmed: 10837075
Int J Cancer. 2017 Feb 15;140(4):973-982
pubmed: 27861852
J Immunol Res. 2018 Dec 19;2018:4325874
pubmed: 30662919
J Urol. 1976 Aug;116(2):180-3
pubmed: 820877
Clin Cancer Res. 2003 Dec 1;9(16 Pt 1):5902-8
pubmed: 14676113
Semin Oncol. 2015 Apr;42(2):316-28
pubmed: 25843736
J Urol. 2000 Apr;163(4):1124-9
pubmed: 10737480
Am J Cancer Res. 2019 Mar 01;9(3):562-573
pubmed: 30949410
Clin Cancer Res. 2006 Apr 1;12(7 Pt 2):2337s-2341s
pubmed: 16609055
J Immunol. 2003 Oct 1;171(7):3467-74
pubmed: 14500642
J Pharm Pharm Sci. 2007;10(2):144-52
pubmed: 17706173
Clin Cancer Res. 2021 Feb 1;27(3):689-703
pubmed: 33122346