Profile of Prescription Medication in an Internal Medicine Ward.

internal medicine ward older adults polypharmacy

Journal

Healthcare (Basel, Switzerland)
ISSN: 2227-9032
Titre abrégé: Healthcare (Basel)
Pays: Switzerland
ID NLM: 101666525

Informations de publication

Date de publication:
10 Jun 2021
Historique:
received: 27 04 2021
revised: 06 06 2021
accepted: 08 06 2021
entrez: 2 7 2021
pubmed: 3 7 2021
medline: 3 7 2021
Statut: epublish

Résumé

Aging-related loss of resilience associated with the lack of evidence regarding the therapeutic efficacy of medicines can prompt a lack of efficacy of treatments and multiple prescriptions. This work aims to characterize the medication profile of Portuguese older adult inpatients and explore the relationship between hospitalization days and the consumption of medicines. A retrospective data analysis study in older patients who were admitted to a medical internal medicine ward during 2019. The median age of the 616 patients included was 85 years. During the hospitalized period, patients took on average 18.08 medicines. The most prescribed drugs belong to the subgroup of (a) anti-thrombotic agents (6.7%), with enoxaparin being the most prescribed, (b) other analgesics and antipyretics (6.6%), paracetamol being the most frequent, and (c) the Angiotensin Conversion Enzyme Inhibitor (ACE) (6.5%), captopril being the most frequent. The high number of prescriptions in older adults during their hospitalization suggests the need of changing therapeutics to achieve a better efficacy of treatment, which corroborates the hypothesis that the lack of scientific evidence concerning the risk/benefits of many medical therapies in older adults can make it difficult to achieve good clinical outcomes and promote the wastage of health resources.

Identifiants

pubmed: 34200609
pii: healthcare9060704
doi: 10.3390/healthcare9060704
pmc: PMC8229020
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Fundação para a Ciência e a Tecnologia
ID : PTDC/MED-FAR/31598/2017

Références

Clin Interv Aging. 2018 Dec 28;14:65-72
pubmed: 30643395
J Clin Pharm Ther. 2018 Apr;43(2):232-239
pubmed: 28990244
Perm J. 2020;24:
pubmed: 31905333
Br J Clin Pharmacol. 2015 Oct;80(4):796-807
pubmed: 25619317
Arch Gerontol Geriatr. 2017 Sep;72:99-102
pubmed: 28618323
Contemp Clin Trials. 2021 Jan;100:106124
pubmed: 32858228
J Clin Pharm Ther. 2017 Apr;42(2):195-200
pubmed: 28155237
PLoS One. 2018 May 3;13(5):e0195949
pubmed: 29723249
Age Ageing. 2012 Nov;41(6):771-6
pubmed: 22456465
PLoS One. 2019 Jul 26;14(7):e0219898
pubmed: 31348784
Arch Intern Med. 2004 Oct 11;164(18):1957-9
pubmed: 15477428
Eur J Hosp Pharm. 2018 Nov;25(6):310-316
pubmed: 31157048
Eur Respir J. 2014 Oct;44(4):1055-68
pubmed: 25142482
Br J Clin Pharmacol. 2015 Dec;80(6):1254-68
pubmed: 27006985
Br J Clin Pharmacol. 2020 Oct;86(10):1904-1911
pubmed: 31321798
Eur J Clin Pharmacol. 2015 Jul;71(7):861-75
pubmed: 25967540
Rev Clin Esp (Barc). 2016 May;216(4):205-21
pubmed: 26899140
Ageing Res Rev. 2010 Oct;9(4):384-98
pubmed: 20478411

Auteurs

Carla Perpétuo (C)

Research Unit for Inland Development, Polytechnic Institute of Guarda (UDI-IPG), 6300-559 Guarda, Portugal.
Local Health Unit of Guarda, 6300-035 Guarda, Portugal.

Ana I Plácido (AI)

Local Health Unit of Guarda, 6300-035 Guarda, Portugal.
Institute of Biomedicine (iBiMED-UA), Department of Medical Sciences, University of Aveiro, 3810-193 Aveiro, Portugal.

Jorge Aperta (J)

Research Unit for Inland Development, Polytechnic Institute of Guarda (UDI-IPG), 6300-559 Guarda, Portugal.
Local Health Unit of Guarda, 6300-035 Guarda, Portugal.

Maria Teresa Herdeiro (MT)

Institute of Biomedicine (iBiMED-UA), Department of Medical Sciences, University of Aveiro, 3810-193 Aveiro, Portugal.

Fátima Roque (F)

Research Unit for Inland Development, Polytechnic Institute of Guarda (UDI-IPG), 6300-559 Guarda, Portugal.
Health Science Research Center (CICS-UBI), University of Beira Interior, 6201-001 Covilhã, Portugal.

Classifications MeSH