Early Life Wheeze and Risk Factors for Asthma-A Revisit at Age 7 in the GEWAC-Cohort.

allergic sensitization asthma preschool wheeze rhinovirus wheeze

Journal

Children (Basel, Switzerland)
ISSN: 2227-9067
Titre abrégé: Children (Basel)
Pays: Switzerland
ID NLM: 101648936

Informations de publication

Date de publication:
08 Jun 2021
Historique:
received: 06 05 2021
revised: 02 06 2021
accepted: 03 06 2021
entrez: 2 7 2021
pubmed: 3 7 2021
medline: 3 7 2021
Statut: epublish

Résumé

One third of all toddlers are in need of medical care because of acute wheeze and many of these children have persistent asthma at school age. Our aims were to assess risk factors for and the prevalence of asthma at age 7 in a cohort of children suffering from an acute wheezing episode as toddlers. A total of 113 children, included during an acute wheezing episode (cases), and 54 healthy controls were followed prospectively from early pre-school age to 7 years. The protocol included questionnaires, ACT, FeNO, nasopharyngeal virus samples, blood sampling for cell count, vitamin D levels, and IgE to food and airborne allergens. The prevalence of asthma at age 7 was 70.8% among cases and 1.9% among controls (

Identifiants

pubmed: 34201058
pii: children8060488
doi: 10.3390/children8060488
pmc: PMC8229161
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Idun Holmdahl (I)

Astrid Lindgren's Children's Hospital, Karolinska University Hospital, 171 64 Stockholm, Sweden.
Department of Women's and Children's Health, Karolinska Institutet, 171 77 Stockholm, Sweden.

Anastasia Filiou (A)

Astrid Lindgren's Children's Hospital, Karolinska University Hospital, 171 64 Stockholm, Sweden.
Department of Women's and Children's Health, Karolinska Institutet, 171 77 Stockholm, Sweden.

Katarina Stenberg Hammar (K)

Astrid Lindgren's Children's Hospital, Karolinska University Hospital, 171 64 Stockholm, Sweden.
Department of Women's and Children's Health, Karolinska Institutet, 171 77 Stockholm, Sweden.

Anna Asarnoj (A)

Astrid Lindgren's Children's Hospital, Karolinska University Hospital, 171 64 Stockholm, Sweden.
Department of Women's and Children's Health, Karolinska Institutet, 171 77 Stockholm, Sweden.

Magnus P Borres (MP)

Department of Women's and Children's Health, Uppsala University, 752 36 Uppsala, Sweden.

Marianne van Hage (M)

Department of Medicine Solna, Division of Immunology and Allergy, Karolinska Institutet and Karolinska University Hospital, 171 76 Stockholm, Sweden.

Gunilla Hedlin (G)

Astrid Lindgren's Children's Hospital, Karolinska University Hospital, 171 64 Stockholm, Sweden.
Department of Women's and Children's Health, Karolinska Institutet, 171 77 Stockholm, Sweden.

Cilla Söderhäll (C)

Astrid Lindgren's Children's Hospital, Karolinska University Hospital, 171 64 Stockholm, Sweden.
Department of Women's and Children's Health, Karolinska Institutet, 171 77 Stockholm, Sweden.

Jon R Konradsen (JR)

Astrid Lindgren's Children's Hospital, Karolinska University Hospital, 171 64 Stockholm, Sweden.
Department of Women's and Children's Health, Karolinska Institutet, 171 77 Stockholm, Sweden.

Classifications MeSH