Transient Reduction of FMD-Response and L-Arginine Accompanied by Increased Levels of E-Selectin, VCAM, and ICAM after Prolonged Strenuous Exercise.

E-selectin FMD ICAM-1 L-arginine NO VCAM-1 endothelium inflammation ironman triathlon

Journal

Sports (Basel, Switzerland)
ISSN: 2075-4663
Titre abrégé: Sports (Basel)
Pays: Switzerland
ID NLM: 101722684

Informations de publication

Date de publication:
17 Jun 2021
Historique:
received: 30 04 2021
revised: 14 06 2021
accepted: 16 06 2021
entrez: 2 7 2021
pubmed: 3 7 2021
medline: 3 7 2021
Statut: epublish

Résumé

We assessed endothelial function by flow-mediated dilatation (FMD), levels of the NO-precursor L-arginine, and markers of endothelial inflammation before, at the finish line, and one week after the Norseman Xtreme triathlon. The race is an Ironman distance triathlon with a total elevation of 5200 m. Nine male participants were included. They completed the race in 14.5 (13.4-15.3) h. FMD was significantly reduced to 3.1 (2.1-5.0)% dilatation compared to 8.7 (8.2-9.3)% dilatation before the race (

Identifiants

pubmed: 34204566
pii: sports9060086
doi: 10.3390/sports9060086
pmc: PMC8234080
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Aker BioMarine Antarctic AS

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Auteurs

Christoffer Nyborg (C)

Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, 0318 Oslo, Norway.
Department of Vascular Surgery, Oslo University Hospital, 0424 Oslo, Norway.

Helene Støle Melsom (HS)

Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, 0318 Oslo, Norway.
Department of Vascular Surgery, Oslo University Hospital, 0424 Oslo, Norway.

Martin Bonnevie-Svendsen (M)

Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, 0318 Oslo, Norway.
Department of Vascular Surgery, Oslo University Hospital, 0424 Oslo, Norway.

Jørgen Melau (J)

Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, 0318 Oslo, Norway.
Department of Vascular Surgery, Oslo University Hospital, 0424 Oslo, Norway.
Department of Prehospital Care, Vestfold Hospital Trust, 3103 Toensberg, Norway.

Ingebjørg Seljeflot (I)

Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, 0318 Oslo, Norway.
Center for Clinical Heart Research, Department of Cardiology, Oslo University Hospital, 0424 Oslo, Norway.

Jonny Hisdal (J)

Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, 0318 Oslo, Norway.
Department of Vascular Surgery, Oslo University Hospital, 0424 Oslo, Norway.

Classifications MeSH