Multidisciplinary Approach for Hypothalamic Obesity in Children and Adolescents: A Preliminary Study.
BMI
hypothalamic obesity
metformin
weight gain
Journal
Children (Basel, Switzerland)
ISSN: 2227-9067
Titre abrégé: Children (Basel)
Pays: Switzerland
ID NLM: 101648936
Informations de publication
Date de publication:
22 Jun 2021
22 Jun 2021
Historique:
received:
11
05
2021
revised:
15
06
2021
accepted:
19
06
2021
entrez:
2
7
2021
pubmed:
3
7
2021
medline:
3
7
2021
Statut:
epublish
Résumé
Hypothalamic obesity (HO) is delineated by an inexorable weight gain in subjects with hypothalamic disorder (congenital or acquired). The aim of the present study was to evaluate the effect of a multidisciplinary approach on weight trend and metabolic outcome in children and adolescents with hypothalamic disease who were overweight or obese. Thirteen patients (aged 8.1-16.1 years) received a personalized diet, accelerometer-based activity monitoring, and psychological assessment. Height, weight, body mass index (BMI), and serum metabolic parameters were assessed at baseline (T0) and after six months (T1). Metformin was introduced at T1 in four subjects who were then re-evaluated after six months (T2). At T1, weight gain was significantly reduced compared with T0 (0.29 ± 0.79 kg/month vs. 0.84 ± 0.55 kg/month,
Identifiants
pubmed: 34206290
pii: children8070531
doi: 10.3390/children8070531
pmc: PMC8304472
pii:
doi:
Types de publication
Journal Article
Langues
eng
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