BRENDA-Score, a Highly Significant, Internally and Externally Validated Prognostic Marker for Metastatic Recurrence: Analysis of 10,449 Primary Breast Cancer Patients.

BRENDA breast cancer follow up prediction risk score

Journal

Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829

Informations de publication

Date de publication:
22 Jun 2021
Historique:
received: 22 04 2021
revised: 16 06 2021
accepted: 17 06 2021
entrez: 2 7 2021
pubmed: 3 7 2021
medline: 3 7 2021
Statut: epublish

Résumé

Background Current research in breast cancer focuses on individualization of local and systemic therapies with adequate escalation or de-escalation strategies. As a result, about two-thirds of breast cancer patients can be cured, but up to one-third eventually develop metastatic disease, which is considered incurable with currently available treatment options. This underscores the importance to develop a metastatic recurrence score to escalate or de-escalate treatment strategies. Patients and methods Data from 10,499 patients were available from 17 clinical cancer registries (BRENDA-project [

Identifiants

pubmed: 34206581
pii: cancers13133121
doi: 10.3390/cancers13133121
pmc: PMC8268855
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : German Federal Ministry of Education and Research
ID : BMBF-Grant-01ZP0505

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Auteurs

Manfred Wischnewsky (M)

FB Mathematik u. Informatik, Universität Bremen, Bibliothekar. 1, 28359 Bremen, Germany.

Lukas Schwentner (L)

Frauenklinik Universität Ulm, Prittwitzstr. 43, 89075 Ulm, Germany.

Joachim Diessner Diessner (JD)

Universitätsfrauenklinik Würzburg, Josef-Schneider-Str. 4, 97080 Würzburg, Germany.

Amelie De Gregorio (A)

Frauenklinik Universität Ulm, Prittwitzstr. 43, 89075 Ulm, Germany.

Ralf Joukhadar (R)

Universitätsfrauenklinik Würzburg, Josef-Schneider-Str. 4, 97080 Würzburg, Germany.

Dayan Davut (D)

Frauenklinik Universität Ulm, Prittwitzstr. 43, 89075 Ulm, Germany.

Jessica Salmen (J)

Universitätsfrauenklinik Würzburg, Josef-Schneider-Str. 4, 97080 Würzburg, Germany.

Inga Bekes (I)

Frauenklinik Universität Ulm, Prittwitzstr. 43, 89075 Ulm, Germany.

Matthias Kiesel (M)

Universitätsfrauenklinik Würzburg, Josef-Schneider-Str. 4, 97080 Würzburg, Germany.

Max Müller-Reiter (M)

Universitätsfrauenklinik Würzburg, Josef-Schneider-Str. 4, 97080 Würzburg, Germany.

Maria Blettner (M)

Institut für Medizinische Biometrie, Epidemiologie und Informatik, Universitätsmedizin Mainz, 55131 Mainz, Germany.

Regine Wolters (R)

FB Mathematik u. Informatik, Universität Bremen, Bibliothekar. 1, 28359 Bremen, Germany.

Wolfgang Janni (W)

Frauenklinik Universität Ulm, Prittwitzstr. 43, 89075 Ulm, Germany.

Rolf Kreienberg (R)

Frauenklinik Universität Ulm, Prittwitzstr. 43, 89075 Ulm, Germany.

Achim Wöckel (A)

Universitätsfrauenklinik Würzburg, Josef-Schneider-Str. 4, 97080 Würzburg, Germany.

Florian Ebner (F)

Frauenklinik Universität Ulm, Prittwitzstr. 43, 89075 Ulm, Germany.
Helios Amper Klinikum Dachau, Krankenhausstr. 15, 85221 Dachau, Germany.

Classifications MeSH