KI and WU Polyomavirus in Respiratory Samples of SARS-CoV-2 Infected Patients.

Karolinska Institutet polyomavirus NCCR sequencing SARS-CoV-2 Washington University polyomavirus co-infection oropharyngeal swab

Journal

Microorganisms
ISSN: 2076-2607
Titre abrégé: Microorganisms
Pays: Switzerland
ID NLM: 101625893

Informations de publication

Date de publication:
09 Jun 2021
Historique:
received: 11 05 2021
revised: 01 06 2021
accepted: 08 06 2021
entrez: 2 7 2021
pubmed: 3 7 2021
medline: 3 7 2021
Statut: epublish

Résumé

Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) has been declared a global pandemic. Our goal was to determine whether co-infections with respiratory polyomaviruses, such as Karolinska Institutet polyomavirus (KIPyV) and Washington University polyomavirus (WUPyV) occur in SARS-CoV-2 infected patients. Oropharyngeal swabs from 150 individuals, 112 symptomatic COVID-19 patients and 38 healthcare workers not infected by SARS-CoV-2, were collected from March 2020 through May 2020 and tested for KIPyV and WUPyV DNA presence. Of the 112 SARS-CoV-2 positive patients, 27 (24.1%) were co-infected with KIPyV, 5 (4.5%) were positive for WUPyV, and 3 (2.7%) were infected simultaneously by KIPyV and WUPyV. Neither KIPyV nor WUPyV DNA was detected in samples of healthcare workers. Significant correlations were found in patients co-infected with SARS-CoV-2 and KIPyV (

Identifiants

pubmed: 34207902
pii: microorganisms9061259
doi: 10.3390/microorganisms9061259
pmc: PMC8229673
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Ministero dell'Istruzione, dell'Università e della Ricerca
ID : RM11916B1DFD19A1

Références

Emerg Infect Dis. 2012 Oct;18(10):1580-8
pubmed: 23017213
N Engl J Med. 2020 Mar 26;382(13):1199-1207
pubmed: 31995857
J Med Virol. 2017 May;89(5):926-930
pubmed: 27704585
J Clin Virol. 2008 Nov;43(3):330-3
pubmed: 18790667
Viruses. 2020 Dec 07;12(12):
pubmed: 33297530
J Neurovirol. 2020 Jun;26(3):311-323
pubmed: 32548750
Infect Genet Evol. 2017 Oct;54:18-38
pubmed: 28634106
Nature. 1986 Nov 13-19;324(6093):163-6
pubmed: 3785382
FEMS Microbiol Rev. 2006 Sep;30(5):760-73
pubmed: 16911043
BMC Infect Dis. 2020 Jul 9;20(1):488
pubmed: 32646445
Pediatr Infect Dis J. 2011 Oct;30(10):918
pubmed: 21915023
Microbiol Immunol. 2011 Jul;55(7):525-30
pubmed: 21545509
Virus Res. 2020 Aug;285:198005
pubmed: 32408156
PLoS One. 2021 May 6;16(5):e0251170
pubmed: 33956882
Zhongguo Dang Dai Er Ke Za Zhi. 2017 Jul;19(7):763-769
pubmed: 28697828
Emerg Infect Dis. 2009 Jan;15(1):107-9
pubmed: 19116066
Cell Res. 2021 Apr;31(4):395-403
pubmed: 33603116
N Engl J Med. 2020 Feb 20;382(8):727-733
pubmed: 31978945
J Clin Virol. 2017 Jan;86:14-19
pubmed: 27893998
Med Microbiol Immunol. 2019 Dec;208(6):845-854
pubmed: 31375897
Nature. 2007 May 17;447(7142):326-9
pubmed: 17507983
J Virol. 2007 Apr;81(8):4130-6
pubmed: 17287263
JAMA. 2020 May 26;323(20):2085-2086
pubmed: 32293646
Viruses. 2020 Aug 26;12(9):
pubmed: 32858801
J Med Virol. 2021 Feb;93(2):886-891
pubmed: 32697357
PLoS Pathog. 2007 May 4;3(5):e64
pubmed: 17480120
J Med Virol. 2011 Aug;83(8):1446-50
pubmed: 21678449
J Virol Methods. 2009 Dec;162(1-2):69-74
pubmed: 19646480
APMIS. 2013 Aug;121(8):746-54
pubmed: 23782405
Viruses. 2021 Jan 18;13(1):
pubmed: 33477649
Int J Infect Dis. 2021 Apr;105:617-620
pubmed: 33640570

Auteurs

Carla Prezioso (C)

Department of Public Health and Infectious Diseases, "Sapienza" University of Rome, 00185 Rome, Italy.
IRCSS San Raffaele Pisana, Microbiology of Chronic Neuro-Degenerative Pathologies, 00163 Rome, Italy.

Ugo Moens (U)

Department of Medical Biology, Faculty of Health Sciences, University of Tromsø-The Arctic University of Norway, 9037 Tromsø, Norway.

Giuseppe Oliveto (G)

Laboratory of Microbiology and Virology, Department of Molecular Medicine, "Sapienza" University of Rome, 00161 Rome, Italy.
Microbiology and Virology Unit, "Sapienza" University Hospital "Policlinico Umberto I", 00161 Rome, Italy.
Istituto Pasteur Italia, 00161 Rome, Italy.

Gabriele Brazzini (G)

Department of Public Health and Infectious Diseases, "Sapienza" University of Rome, 00185 Rome, Italy.

Francesca Piacentini (F)

Department of Public Health and Infectious Diseases, "Sapienza" University of Rome, 00185 Rome, Italy.

Federica Frasca (F)

Laboratory of Microbiology and Virology, Department of Molecular Medicine, "Sapienza" University of Rome, 00161 Rome, Italy.
Istituto Pasteur Italia, 00161 Rome, Italy.

Agnese Viscido (A)

Laboratory of Microbiology and Virology, Department of Molecular Medicine, "Sapienza" University of Rome, 00161 Rome, Italy.
Microbiology and Virology Unit, "Sapienza" University Hospital "Policlinico Umberto I", 00161 Rome, Italy.

Mirko Scordio (M)

Laboratory of Microbiology and Virology, Department of Molecular Medicine, "Sapienza" University of Rome, 00161 Rome, Italy.
Istituto Pasteur Italia, 00161 Rome, Italy.

Giuliana Guerrizio (G)

Laboratory of Microbiology and Virology, Department of Molecular Medicine, "Sapienza" University of Rome, 00161 Rome, Italy.
Microbiology and Virology Unit, "Sapienza" University Hospital "Policlinico Umberto I", 00161 Rome, Italy.

Donatella Maria Rodio (DM)

Laboratory of Microbiology and Virology, Department of Molecular Medicine, "Sapienza" University of Rome, 00161 Rome, Italy.
Microbiology and Virology Unit, "Sapienza" University Hospital "Policlinico Umberto I", 00161 Rome, Italy.

Alessandra Pierangeli (A)

Laboratory of Microbiology and Virology, Department of Molecular Medicine, "Sapienza" University of Rome, 00161 Rome, Italy.
Istituto Pasteur Italia, 00161 Rome, Italy.

Gabriella d'Ettorre (G)

Department of Public Health and Infectious Diseases, "Sapienza" University of Rome, 00185 Rome, Italy.

Ombretta Turriziani (O)

Laboratory of Microbiology and Virology, Department of Molecular Medicine, "Sapienza" University of Rome, 00161 Rome, Italy.
Microbiology and Virology Unit, "Sapienza" University Hospital "Policlinico Umberto I", 00161 Rome, Italy.

Guido Antonelli (G)

Laboratory of Microbiology and Virology, Department of Molecular Medicine, "Sapienza" University of Rome, 00161 Rome, Italy.
Microbiology and Virology Unit, "Sapienza" University Hospital "Policlinico Umberto I", 00161 Rome, Italy.
Istituto Pasteur Italia, 00161 Rome, Italy.

Carolina Scagnolari (C)

Laboratory of Microbiology and Virology, Department of Molecular Medicine, "Sapienza" University of Rome, 00161 Rome, Italy.
Istituto Pasteur Italia, 00161 Rome, Italy.

Valeria Pietropaolo (V)

Department of Public Health and Infectious Diseases, "Sapienza" University of Rome, 00185 Rome, Italy.
Microbiology and Virology Unit, "Sapienza" University Hospital "Policlinico Umberto I", 00161 Rome, Italy.

Classifications MeSH