Nanomaterials in Skin Regeneration and Rejuvenation.
cellular mechanisms
nanomaterials
regenerative medicine
skin
stem cells
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
30 Jun 2021
30 Jun 2021
Historique:
received:
24
05
2021
revised:
18
06
2021
accepted:
28
06
2021
entrez:
2
7
2021
pubmed:
3
7
2021
medline:
22
7
2021
Statut:
epublish
Résumé
Skin is the external part of the human body; thus, it is exposed to outer stimuli leading to injuries and damage, due to being the tissue mostly affected by wounds and aging that compromise its protective function. The recent extension of the average lifespan raises the interest in products capable of counteracting skin related health conditions. However, the skin barrier is not easy to permeate and could be influenced by different factors. In the last decades an innovative pharmacotherapeutic approach has been possible thanks to the advent of nanomedicine. Nanodevices can represent an appropriate formulation to enhance the passive penetration, modulate drug solubility and increase the thermodynamic activity of drugs. Here, we summarize the recent nanotechnological approaches to maintain and replace skin homeostasis, with particular attention to nanomaterials applications on wound healing, regeneration and rejuvenation of skin tissue. The different nanomaterials as nanofibers, hydrogels, nanosuspensions, and nanoparticles are described and in particular we highlight their main chemical features that are useful in drug delivery and tissue regeneration.
Identifiants
pubmed: 34209468
pii: ijms22137095
doi: 10.3390/ijms22137095
pmc: PMC8268279
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Références
Asian J Pharm Sci. 2019 Mar;14(2):130-143
pubmed: 32104445
Biomed Mater. 2021 Feb 11;:
pubmed: 33571971
Beilstein J Nanotechnol. 2018 Apr 3;9:1050-1074
pubmed: 29719757
Materials (Basel). 2015 Aug 11;8(8):5154-5193
pubmed: 28793497
FEMS Microbiol Lett. 2008 Feb;279(1):71-6
pubmed: 18081843
J Cell Sci. 2005 Feb 1;118(Pt 3):485-96
pubmed: 15657080
Adv Wound Care (New Rochelle). 2018 Feb 1;7(2):29-45
pubmed: 29392092
Physiol Res. 2019 Dec 30;68(Suppl 4):S501-S508
pubmed: 32118482
Nanotoxicology. 2021 Feb;15(1):131-144
pubmed: 33370537
Future Sci OA. 2020 Aug 06;6(10):FSO613
pubmed: 33312696
Molecules. 2020 Dec 09;25(24):
pubmed: 33317120
Nat Commun. 2021 Mar 15;12(1):1670
pubmed: 33723267
Am J Transl Res. 2019 Jul 15;11(7):3919-3931
pubmed: 31396309
Am J Surg. 1998 Aug;176(2A Suppl):26S-38S
pubmed: 9777970
PLoS One. 2018 Mar 29;13(3):e0194458
pubmed: 29596429
Acta Pharm Sin B. 2019 Jan;9(1):97-106
pubmed: 30766781
J Control Release. 2016 Sep 28;238:114-122
pubmed: 27473766
Pharm Sci Technol Today. 2000 Sep 1;3(9):318-326
pubmed: 10996573
Curr Biol. 2011 Sep 27;21(18):R701-7
pubmed: 21959160
ACS Omega. 2020 Nov 12;5(46):30011-30022
pubmed: 33251437
Wound Repair Regen. 2009 Nov-Dec;17(6):763-71
pubmed: 19903300
Adv Healthc Mater. 2021 Feb;10(3):e2001122
pubmed: 33103384
Mol Pharm. 2019 Sep 3;16(9):3916-3925
pubmed: 31318574
Life Sci. 2021 Mar 1;268:118932
pubmed: 33400933
Photodermatol Photoimmunol Photomed. 2021 Apr 25;:
pubmed: 33896049
Front Bioeng Biotechnol. 2020 Jun 03;8:481
pubmed: 32582653
Br J Dermatol. 2019 Nov;181(5):907-915
pubmed: 30945275
Front Bioeng Biotechnol. 2020 Jul 21;8:643
pubmed: 32793561
Cold Spring Harb Perspect Med. 2014 Feb 01;4(2):
pubmed: 24492848
J Nanobiotechnology. 2021 Feb 24;19(1):53
pubmed: 33627148
Int J Pharm. 2021 Mar 1;596:120213
pubmed: 33493599
World J Exp Med. 2017 Feb 20;7(1):1-10
pubmed: 28261550
Curr Diabetes Rev. 2021;17(4):512-521
pubmed: 33045979
Chem Soc Rev. 2011 Jan;40(1):233-45
pubmed: 20886124
Int Wound J. 2020 Apr;17(2):485-490
pubmed: 31876118
Am J Pathol. 2004 Sep;165(3):741-51
pubmed: 15331399
Mater Sci Eng C Mater Biol Appl. 2021 Jan;118:111542
pubmed: 33255094
Int J Pharm. 2021 Mar 15;597:120207
pubmed: 33524526
Ther Deliv. 2019 Jun 1;10(6):383-396
pubmed: 31184548
Colloids Surf B Biointerfaces. 2020 Dec;196:111301
pubmed: 32871442
Int J Biol Macromol. 2021 Feb 15;170:728-750
pubmed: 33387543
Int J Biol Macromol. 2016 Apr;85:29-39
pubmed: 26718866
Br J Dermatol. 2019 Nov;181(5):884
pubmed: 31259384
Biogerontology. 2009 Oct;10(5):549-64
pubmed: 19031007
J Biol Chem. 2014 Nov 14;289(46):32253-32265
pubmed: 25266724
Nanotoxicology. 2010 Dec;4:364-81
pubmed: 20925445
Int J Mol Sci. 2019 Apr 29;20(9):
pubmed: 31036793
Adv Sci (Weinh). 2018 Feb 22;5(5):1700527
pubmed: 29876202
World J Stem Cells. 2020 Jul 26;12(7):604-611
pubmed: 32843916
Colloids Surf B Biointerfaces. 2020 May;189:110855
pubmed: 32101788
J Pharm Sci. 2021 May;110(5):2250-2261
pubmed: 33539871
Prog Biomater. 2018 Mar;7(1):1-21
pubmed: 29446015
J Nanobiotechnology. 2018 Jan 10;16(1):2
pubmed: 29321021
Trials. 2021 Jan 6;22(1):10
pubmed: 33407796
Pharmaceutics. 2020 Feb 03;12(2):
pubmed: 32028579
J Biomater Appl. 2020 Aug;35(2):287-298
pubmed: 32443958
J Control Release. 2013 May 10;167(3):301-14
pubmed: 23454133
Front Bioeng Biotechnol. 2020 Sep 25;8:577557
pubmed: 33102462
Nano Today. 2015 Aug;10(4):487-510
pubmed: 26640510
Mol Biol Rep. 2018 Dec;45(6):2857-2867
pubmed: 30094529
Pharm Res. 2019 Jun 19;36(8):122
pubmed: 31218556
AAPS PharmSciTech. 2010 Sep;11(3):1164-70
pubmed: 20661676
Cell Prolif. 2016 Oct;49(5):568-78
pubmed: 27452632
Eur J Pharm Sci. 2001 Sep;14(2):101-14
pubmed: 11500256
Int J Nanomedicine. 2015 Dec 07;10:7307-17
pubmed: 26677321
Pharmaceutics. 2021 Jan 30;13(2):
pubmed: 33573313
Small. 2016 Oct;12(39):5488-5496
pubmed: 27562146
Nanomedicine. 2015 Aug;11(6):1551-73
pubmed: 25804415
Polymers (Basel). 2021 Mar 10;13(6):
pubmed: 33802198
R Soc Open Sci. 2020 Sep 30;7(9):201266
pubmed: 33047067
ACS Biomater Sci Eng. 2021 Apr 12;7(4):1693-1702
pubmed: 33719406
Int J Pharm. 2021 Mar 15;597:120311
pubmed: 33539998
J Invest Dermatol. 2012 Mar;132(3 Pt 2):976-84
pubmed: 22170486
Acta Biomater. 2015 Oct;26:236-48
pubmed: 26272777
J Med Chem. 2019 Jul 11;62(13):5923-5943
pubmed: 30735392
Skin Res Technol. 2002 Aug;8(3):148-54
pubmed: 12236883
Molecules. 2019 Apr 17;24(8):
pubmed: 30999678
Sci Rep. 2014 Sep 16;4:6373
pubmed: 25224681
Drug Dev Ind Pharm. 2020 Oct;46(10):1613-1621
pubmed: 32806984
J Control Release. 2020 Aug 10;324:505-521
pubmed: 32464152
J Mater Chem B. 2021 Apr 14;9(14):3106-3130
pubmed: 33885618
Acta Biomater. 2021 Apr 15;125:231-241
pubmed: 33607306
Curr Drug Deliv. 2007 Jul;4(3):195-204
pubmed: 17627493
AAPS PharmSciTech. 2013 Mar;14(1):254-64
pubmed: 23274734
Molecules. 2020 Oct 06;25(19):
pubmed: 33036163
Carcinogenesis. 2005 Oct;26(10):1657-67
pubmed: 15905207
Front Cell Dev Biol. 2021 Mar 25;9:660571
pubmed: 33842486
J Nanobiotechnology. 2021 Feb 5;19(1):38
pubmed: 33546702
Nat Nanotechnol. 2021 Mar;16(3):266-276
pubmed: 33712737
Aesthetic Plast Surg. 2003 Sep-Oct;27(5):411-7
pubmed: 14648065
ACS Biomater Sci Eng. 2020 Feb 10;6(2):1124-1134
pubmed: 33464871
FASEB J. 1990 Apr 1;4(6):1577-90
pubmed: 2180767
ACS Nano. 2009 Jan 27;3(1):16-20
pubmed: 19206243
Int J Med Sci. 2020 Apr 7;17(8):1030-1042
pubmed: 32410832
Mater Sci Eng C Mater Biol Appl. 2017 Dec 1;81:459-468
pubmed: 28887998
Physiol Res. 2019 Dec 30;68(Suppl 4):S385-S388
pubmed: 32118468
Appl Microbiol Biotechnol. 2018 May;102(10):4305-4318
pubmed: 29589095
Bioact Mater. 2021 Jan 09;6(7):2070-2088
pubmed: 33511308
J Ginseng Res. 2018 Jul;42(3):327-333
pubmed: 29983614
Nanoscale. 2021 Apr 7;13(13):6531-6537
pubmed: 33885532
Ann Dermatol. 2013 Aug;25(3):278-84
pubmed: 24003268
J Nanosci Nanotechnol. 2014 Jan;14(1):990-1006
pubmed: 24730316
Colloids Surf B Biointerfaces. 2021 Mar;199:111502
pubmed: 33387795
Nurs Clin North Am. 2005 Jun;40(2):191-205, v
pubmed: 15924889
Cells. 2020 Nov 24;9(12):
pubmed: 33255167
Int J Pharm. 2021 Jun 15;603:120698
pubmed: 33989750
Nanomaterials (Basel). 2020 Sep 10;10(9):
pubmed: 32927642
Int J Biol Macromol. 2020 Dec 1;164:2818-2830
pubmed: 32853619
Indian J Dermatol Venereol Leprol. 2017 Jan-Feb;83(1):121-124
pubmed: 27779145
Skin Res Technol. 2016 Aug;22(3):295-304
pubmed: 26336894
ACS Biomater Sci Eng. 2021 Jan 11;7(1):335-349
pubmed: 33371671
Skin Pharmacol Physiol. 2006;19(2):106-21
pubmed: 16685150
Acta Biomater. 2011 Apr;7(4):1702-9
pubmed: 21095244
Sci Rep. 2018 Sep 12;8(1):13674
pubmed: 30209256
Aging Cell. 2007 Aug;6(4):439-52
pubmed: 17635170
J Pharm (Cairo). 2018 Mar 27;2018:3420204
pubmed: 29785318
Curr Drug Deliv. 2005 Jan;2(1):23-33
pubmed: 16305405
Biomater Sci. 2020 Dec 15;8(24):6957-6968
pubmed: 33103177
Am J Pathol. 2006 Jun;168(6):1861-8
pubmed: 16723701
Biochem Biophys Res Commun. 2019 Oct 1;517(4):684-690
pubmed: 31400855
Int J Pharm. 2020 Aug 30;586:119543
pubmed: 32561307
Pharmaceutics. 2021 Feb 28;13(3):
pubmed: 33670973