Huntingtin and the Synapse.

Huntingtin Huntington disease autophagy endocytosis excitotoxicity exocytosis intracellular tranport synaptic plastcity

Journal

Frontiers in cellular neuroscience
ISSN: 1662-5102
Titre abrégé: Front Cell Neurosci
Pays: Switzerland
ID NLM: 101477935

Informations de publication

Date de publication:
2021
Historique:
received: 31 03 2021
accepted: 24 05 2021
entrez: 2 7 2021
pubmed: 3 7 2021
medline: 3 7 2021
Statut: epublish

Résumé

Huntington disease (HD) is a monogenic disease that results in a combination of motor, psychiatric and cognitive symptoms. HD is caused by a CAG trinucleotide repeat expansion in the huntingtin (

Identifiants

pubmed: 34211373
doi: 10.3389/fncel.2021.689332
pmc: PMC8239291
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

689332

Informations de copyright

Copyright © 2021 Barron, Hurley and Parsons.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Jessica C Barron (JC)

Division of Biomedical Sciences, Faculty of Medicine, Memorial University, St. John's, NL, Canada.

Emily P Hurley (EP)

Division of Biomedical Sciences, Faculty of Medicine, Memorial University, St. John's, NL, Canada.

Matthew P Parsons (MP)

Division of Biomedical Sciences, Faculty of Medicine, Memorial University, St. John's, NL, Canada.

Classifications MeSH