Sleep disturbances following traumatic brain injury are associated with poor neurobehavioral outcomes in US military service members and veterans.


Journal

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine
ISSN: 1550-9397
Titre abrégé: J Clin Sleep Med
Pays: United States
ID NLM: 101231977

Informations de publication

Date de publication:
01 12 2021
Historique:
pubmed: 4 7 2021
medline: 24 12 2021
entrez: 3 7 2021
Statut: ppublish

Résumé

This study examined whether sleep disturbances were associated with neurobehavioral outcome following a traumatic brain injury (TBI) in a well characterized group of service members and veterans. Six hundred and six participants were enrolled into the Defense and Veterans Brain Injury Center, 15-Year Longitudinal TBI study. All participants completed a battery of tests measuring self-reported sleep disturbances, neurobehavioral symptoms, and posttraumatic stress disorder symptoms. Data were analyzed using analysis of variance with post hoc comparisons. Four groups were analyzed separately: uncomplicated mild TBI; complicated mild, moderate, severe, or penetrating combined TBI; injured controls (ie, orthopedic or soft-tissue injury without TBI); and noninjured controls. A higher proportion of the mild TBI group reported moderate-severe sleep disturbances (66.5%) compared to the injured control group (54.9%), combined TBI (47.5%), and noninjured control groups (34.3%). Participants classified as having Poor Sleep had significantly worse scores on the majority of TBI-Quality of Life scales compared to those classified as having Good Sleep, regardless of TBI severity or the presence of TBI. There was a significant interaction between sleep disturbances and posttraumatic stress disorder. While sleep disturbances and posttraumatic stress disorder by themselves were significant factors associated with worse outcome, both factors combined resulted in worse outcome than either singularly. Regardless of group (injured or noninjured control), sleep disturbances were common and were associated with significantly worse neurobehavioral functioning. When experienced concurrently with posttraumatic stress disorder, sleep disturbances pose significant burden to service members and veterans. Pattinson CL, Brickell TA, Bailie J, et al. Sleep disturbances following traumatic brain injury are associated with poor neurobehavioral outcomes in US military service members and veterans.

Identifiants

pubmed: 34216198
pii: jcsm.9454
doi: 10.5664/jcsm.9454
pmc: PMC8726371
doi:

Types de publication

Journal Article Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

2425-2438

Informations de copyright

© 2021 American Academy of Sleep Medicine.

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Auteurs

Cassandra L Pattinson (CL)

University of Queensland, Institute for Social Science Research, Brisbane, Queensland, Australia.

Tracey A Brickell (TA)

Defense and Veterans Brain Injury Center, Silver Spring, Maryland.
Walter Reed National Military Medical Center, Bethesda, Maryland.
National Intrepid Center of Excellence, Bethesda, Maryland.
Uniformed Services University of the Health Sciences, Bethesda, Maryland.
General Dynamics Information Technology, Falls Church, Virginia.
Centre of Excellence on Post-Traumatic Stress Disorder, Ottawa, Ontario, Canada.

Jason Bailie (J)

Defense and Veterans Brain Injury Center, Silver Spring, Maryland.
General Dynamics Information Technology, Falls Church, Virginia.
Naval Hospital Camp Pendleton, Oceanside, California.

Lars Hungerford (L)

Defense and Veterans Brain Injury Center, Silver Spring, Maryland.
General Dynamics Information Technology, Falls Church, Virginia.
Naval Medical Center, San Diego, California.

Sara M Lippa (SM)

Walter Reed National Military Medical Center, Bethesda, Maryland.
National Intrepid Center of Excellence, Bethesda, Maryland.

Louis M French (LM)

Defense and Veterans Brain Injury Center, Silver Spring, Maryland.
Walter Reed National Military Medical Center, Bethesda, Maryland.
National Intrepid Center of Excellence, Bethesda, Maryland.
Uniformed Services University of the Health Sciences, Bethesda, Maryland.

Rael T Lange (RT)

Defense and Veterans Brain Injury Center, Silver Spring, Maryland.
Walter Reed National Military Medical Center, Bethesda, Maryland.
National Intrepid Center of Excellence, Bethesda, Maryland.
General Dynamics Information Technology, Falls Church, Virginia.
Centre of Excellence on Post-Traumatic Stress Disorder, Ottawa, Ontario, Canada.
University of British Columbia, Vancouver, Canada.

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