Associations Between Baseline and Longitudinal Semiautomated Quantitative Joint Space Width at the Hip and Incident Hip Osteoarthritis: Data From a Community-Based Cohort.


Journal

Arthritis care & research
ISSN: 2151-4658
Titre abrégé: Arthritis Care Res (Hoboken)
Pays: United States
ID NLM: 101518086

Informations de publication

Date de publication:
12 2022
Historique:
revised: 17 06 2021
received: 13 02 2021
accepted: 01 07 2021
pubmed: 6 7 2021
medline: 21 12 2022
entrez: 5 7 2021
Statut: ppublish

Résumé

To evaluate quantitative joint space width (JSW) at 10-, 30-, and 50-degree locations in relation to incident radiographic and symptomatic hip osteoarthritis (HOA) in a community-based cohort. Data were from Johnston County OA Project participants with supine hip radiographs at each of 4 time points; all had Kellgren/Lawrence (K/L) grades and quantitative JSW. We assessed covariates (age, race, height, weight, body mass index [BMI]) associated with quantitative JSW and hip-level associations between quantitative JSW and HOA over time using sex-stratified and multivariable-adjusted linear mixed models. A cluster analysis with logistic regression estimated associations between quantitative JSW trajectory groups and incident radiographic HOA and symptomatic HOA. At baseline, 397 participants (784 hips, 41% men, 24% Black, mean age 57 years) had a mean BMI of 29 kg/m Hip quantitative JSW demonstrates marked differences in respect to sex, with significant loss over time only in women. Loss of quantitative JSW over time in women and narrower baseline quantitative JSW in men and women were associated with incident radiographic HOA and symptomatic HOA.

Identifiants

pubmed: 34219398
doi: 10.1002/acr.24742
pmc: PMC8727661
mid: NIHMS1721323
doi:

Substances chimiques

4-hexyloxyaniline 39905-57-2

Types de publication

Journal Article Research Support, U.S. Gov't, P.H.S. Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

1978-1988

Subventions

Organisme : NCCDPHP CDC HHS
ID : U01 DP006266
Pays : United States
Organisme : NIAMS NIH HHS
ID : P60 AR030701
Pays : United States
Organisme : ACL HHS
ID : U01DP006266
Pays : United States
Organisme : NIAMS NIH HHS
ID : P60 AR064166
Pays : United States
Organisme : NIAMS NIH HHS
ID : P30 AR072580
Pays : United States
Organisme : NIAMS NIH HHS
ID : P60 AR049465
Pays : United States
Organisme : NCCDPHP CDC HHS
ID : U01 DP003206
Pays : United States

Informations de copyright

© 2021 American College of Rheumatology.

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Auteurs

Amanda E Nelson (AE)

University of North Carolina at Chapel Hill.

Jacquelyn A Smith (JA)

University of North Carolina at Chapel Hill, and Rheumatology Associates, Louisville, Kentucky.

Carolina Alvarez (C)

University of North Carolina at Chapel Hill.

Liubov Arbeeva (L)

University of North Carolina at Chapel Hill.

Jordan B Renner (JB)

University of North Carolina at Chapel Hill.

Louise B Murphy (LB)

Centers for Disease Control and Prevention, Atlanta, Georgia, and Optum Life Sciences, Eden Prairie, Minnesota.

Joanne M Jordan (JM)

University of North Carolina at Chapel Hill.

Yvonne M Golightly (YM)

University of North Carolina at Chapel Hill.

Jeffrey Duryea (J)

Brigham and Women's Hospital, Boston, Massachusetts.

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