Leveraging a matrix of stakeholders to facilitate access to chemotherapy for women's cancers in the Democratic Republic of the Congo.

Biamba Marie Mutombo Hospital Bioventures global health Democratic Republic of the Congo Dikembe Mutombo Foundation South–south collaboration breast cancer cervical cancer chemotherapy conflict and violence-affected country fragile

Journal

Ecancermedicalscience
ISSN: 1754-6605
Titre abrégé: Ecancermedicalscience
Pays: England
ID NLM: 101392236

Informations de publication

Date de publication:
2021
Historique:
received: 18 11 2020
entrez: 5 7 2021
pubmed: 6 7 2021
medline: 6 7 2021
Statut: epublish

Résumé

Cancer incidence is increasing worldwide. Over the next 20 years, the growing proportion of cases in low- and middle-income countries (LMICs) will account for an estimated 70% of all cancers diagnosed. The vast majority of cancer patients in LMICs will require chemotherapy, due to the advanced stage of their disease at the time of initial presentation. Unfortunately, the availability of cancer drugs in these environments is sparse, resulting in premature death and years of life lost. In an effort to lay a foundation for women's cancer control in the Democratic Republic of the Congo (DRC), we implemented a programme which combined workforce development, infrastructure creation and cancer drug access. This manuscript reports on our experience with the latter. A private sector healthcare facility was selected as the programme implementation site. Workforce capacity was developed through a south-south partnership with an African national cancer centre. Cancer drugs were procured through a global cancer medicine access initiative. A new chemotherapy infusion unit was successfully established at the Biamba Marie Mutombo Hospital in Kinshasa, DRC. A team of Congolese healthcare providers was trained at the Cancer Disease Hospital in Zambia to safely and effectively administer chemotherapy for breast and cervical cancer. Over 100 breast and cervical cancer patients have been treated with 337 courses of chemotherapy, without any serious adverse events. Common barriers to cancer drug access and its administration can be eliminated using regional educational resources to build oncologic workforce capacity, private sector healthcare facilities for infrastructure support and pharmaceutical consortiums to procure low-cost cancer medicines. By leveraging a matrix of global, regional and local stakeholders, the prevailing status quo of very limited access to chemotherapy for women's cancers was creatively disrupted in DRC, Africa's largest fragile, conflict and violence-affected country.

Sections du résumé

BACKGROUND BACKGROUND
Cancer incidence is increasing worldwide. Over the next 20 years, the growing proportion of cases in low- and middle-income countries (LMICs) will account for an estimated 70% of all cancers diagnosed. The vast majority of cancer patients in LMICs will require chemotherapy, due to the advanced stage of their disease at the time of initial presentation. Unfortunately, the availability of cancer drugs in these environments is sparse, resulting in premature death and years of life lost. In an effort to lay a foundation for women's cancer control in the Democratic Republic of the Congo (DRC), we implemented a programme which combined workforce development, infrastructure creation and cancer drug access. This manuscript reports on our experience with the latter.
METHODS METHODS
A private sector healthcare facility was selected as the programme implementation site. Workforce capacity was developed through a south-south partnership with an African national cancer centre. Cancer drugs were procured through a global cancer medicine access initiative.
RESULTS RESULTS
A new chemotherapy infusion unit was successfully established at the Biamba Marie Mutombo Hospital in Kinshasa, DRC. A team of Congolese healthcare providers was trained at the Cancer Disease Hospital in Zambia to safely and effectively administer chemotherapy for breast and cervical cancer. Over 100 breast and cervical cancer patients have been treated with 337 courses of chemotherapy, without any serious adverse events.
CONCLUSION CONCLUSIONS
Common barriers to cancer drug access and its administration can be eliminated using regional educational resources to build oncologic workforce capacity, private sector healthcare facilities for infrastructure support and pharmaceutical consortiums to procure low-cost cancer medicines. By leveraging a matrix of global, regional and local stakeholders, the prevailing status quo of very limited access to chemotherapy for women's cancers was creatively disrupted in DRC, Africa's largest fragile, conflict and violence-affected country.

Identifiants

pubmed: 34221117
doi: 10.3332/ecancer.2021.1234
pii: can-15-1234
pmc: PMC8225332
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1234

Informations de copyright

© the authors; licensee ecancermedicalscience.

Déclaration de conflit d'intérêts

None of the authors declare any conflicts of interest.

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Auteurs

Tankoy Gombo YouYou (TG)

Biamba Marie Mutombo Hospital, No. 9777, Boulevard Lumumba, Commune de Masina, Kinshasa, Democratic Republic of the Congo.

Kabongo Mukuta Mathieu (KM)

Biamba Marie Mutombo Hospital, No. 9777, Boulevard Lumumba, Commune de Masina, Kinshasa, Democratic Republic of the Congo.

Michael L Hicks (ML)

Department of Obstetrics and Gynaecology, University of North Carolina at Chapel Hill, 101 Manning Dr, Chapel Hill, NC 27514, USA.
Department of Obstetrics and Gynaecology, University Teaching Hospital - Women and Newborn Hospital, 10101 Nationalist Way, Lusaka, Zambia.
St Mary Mercy Cancer Center 36475 Five Mile Rd, Livonia, MI 48154, USA.
St Joseph Mercy Oakland Cancer Center 44405 Woodward Ave, Suite 202, Pontiac, MI 48324, USA.
McLaren Macomb Medical Center, 1000 Harrington Blvd, Mount Clemens, MI 48043, USA.
https://orcid.org/0000-0002-1819-155X.

Ronda Henry-Tillman (R)

Winthrop P Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, 4301 West Markham, Slot #725, Little Rock, AR 72205, USA.
https://orcid.org/0000-0002-1782-9523.

Alex Mutombo (A)

Biamba Marie Mutombo Hospital, No. 9777, Boulevard Lumumba, Commune de Masina, Kinshasa, Democratic Republic of the Congo.

Mukanya Mpalata Anaclet (MM)

Biamba Marie Mutombo Hospital, No. 9777, Boulevard Lumumba, Commune de Masina, Kinshasa, Democratic Republic of the Congo.

Mulumba Kapuku Sylvain (MK)

Biamba Marie Mutombo Hospital, No. 9777, Boulevard Lumumba, Commune de Masina, Kinshasa, Democratic Republic of the Congo.

Maya M Hicks (MM)

Howard University College of Medicine, 520 W St NW, Washington, DC 20059, USA.
https://orcid.org/0000-0002-1993-3367.

Leeya Pinder (L)

Department of Obstetrics and Gynaecology, University Teaching Hospital - Women and Newborn Hospital, 10101 Nationalist Way, Lusaka, Zambia.
Department of Oncology, University of Washington, 1959 NE Pacific St, Seattle, Washington, DC 98195, USA.
https://orcid.org/0000-0002-8929-7810.

Louis Kanda (L)

Dikembe Mutombo Foundation, 400 Interstate N Pkwy, Suite 1040, Atlanta, GA 30339, USA.

Mirielle Kanda (M)

Dikembe Mutombo Foundation, 400 Interstate N Pkwy, Suite 1040, Atlanta, GA 30339, USA.

Groesbeck P Parham (GP)

Department of Obstetrics and Gynaecology, University of North Carolina at Chapel Hill, 101 Manning Dr, Chapel Hill, NC 27514, USA.
Department of Obstetrics and Gynaecology, University Teaching Hospital - Women and Newborn Hospital, 10101 Nationalist Way, Lusaka, Zambia.
https://orcid.org/0000-0001-5922-5990.

Classifications MeSH