Acousto-optic interaction strengths in optically scattering media using high pressure acoustic pulses.


Journal

Biomedical optics express
ISSN: 2156-7085
Titre abrégé: Biomed Opt Express
Pays: United States
ID NLM: 101540630

Informations de publication

Date de publication:
01 Jun 2021
Historique:
received: 02 02 2021
revised: 26 03 2021
accepted: 07 04 2021
entrez: 5 7 2021
pubmed: 6 7 2021
medline: 6 7 2021
Statut: epublish

Résumé

Ultrasound optical tomography (UOT) is a developing medical imaging technique with the potential to noninvasively image tissue oxygenation at depths of several centimeters in human tissue. To accurately model the UOT imaging, it is necessary the calculate the signal produced by the interaction between ultrasound and light in the scattering medium. In this paper we present a rigorous description for modeling this process for ultrasound pulses in the non-linear regime with peak pressures ranging up to the medical safety limit. Simulation results based on the presented model agree well with measurements performed with fully characterized ultrasound pulses. Our results also indicate that the UOT modeling process can be accurately simplified by disregarding the acoustically induced movement of scatterers. Our results suggest that the explored model and its software implementation can be used as a virtual lab to aid future development of pulses and UOT imaging algorithms.

Identifiants

pubmed: 34221654
doi: 10.1364/BOE.421636
pii: 421636
pmc: PMC8221955
doi:

Types de publication

Journal Article

Langues

eng

Pagination

3196-3213

Informations de copyright

© 2021 Optical Society of America under the terms of the OSA Open Access Publishing Agreement.

Déclaration de conflit d'intérêts

The authors declare that there are no conflicts of interest related to this article.

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Auteurs

David Hill (D)

SpectraCure AB, Gasverksgatan 1, 222 29 Lund, Sweden.
Department of Physics, Lund University, 221 00 Lund, Sweden.

Alexander Bengtsson (A)

Department of Physics, Lund University, 221 00 Lund, Sweden.

Tobias Erlöv (T)

Department of Biomedical Engineering, Lund University, 221 00 Lund, Sweden.

Magnus Cinthio (M)

Department of Biomedical Engineering, Lund University, 221 00 Lund, Sweden.

Stefan Kröll (S)

Department of Physics, Lund University, 221 00 Lund, Sweden.

Classifications MeSH