Is Gardner-Diamond syndrome related to autoimmunity?
Autoerythrocyte sensitization syndrome
Gardner-Diamond syndrome
autoimmunity
systemic lupus erythematosus
Journal
Northern clinics of Istanbul
ISSN: 2536-4553
Titre abrégé: North Clin Istanb
Pays: Turkey
ID NLM: 101684520
Informations de publication
Date de publication:
2021
2021
Historique:
received:
21
02
2020
accepted:
10
04
2021
entrez:
5
7
2021
pubmed:
6
7
2021
medline:
6
7
2021
Statut:
epublish
Résumé
Gardner and Diamond described a clinical picture of painful ecchymosis in the skin and mucous membranes in four female patients and called this entity Gardner-Diamond syndrome (GDS). At present, the exact pathogenesis of the disease is still unknown. In recent years, it has been advocated that antibodies against phosphatidylserine in erythrocyte stroma may cause immune complex and complement activation, leading to this clinical picture. Herein, we found it appropriate to present a case of multiple ecchymotic lesions diagnosed with GDS followed by many autoimmune diseases to draw attention to autoimmune association. As a result of this case presentation and mini-literature review, we think that autoimmunity patients should not be missed in GDS patients.
Identifiants
pubmed: 34222815
doi: 10.14744/nci.2020.97992
pii: NCI-8-310
pmc: PMC8240244
doi:
Types de publication
Case Reports
Langues
eng
Pagination
310-313Informations de copyright
Copyright: © 2021 by Istanbul Northern Anatolian Association of Public Hospitals.
Déclaration de conflit d'intérêts
Conflict of Interest: No conflict of interest was declared by the authors.
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