Evaluating cognitive profiles of patients undergoing clinical amyloid-PET imaging.
Alzheimer’s disease
amyloid PET imaging
cognitive testing
dementia
neuropsychology
Journal
Brain communications
ISSN: 2632-1297
Titre abrégé: Brain Commun
Pays: England
ID NLM: 101755125
Informations de publication
Date de publication:
2021
2021
Historique:
received:
14
10
2020
revised:
06
01
2021
accepted:
25
01
2021
entrez:
5
7
2021
pubmed:
6
7
2021
medline:
6
7
2021
Statut:
epublish
Résumé
Episodic memory impairment and brain amyloid-beta are two of the main hallmarks of Alzheimer's Disease. In the clinical setting, these are often evaluated through neuropsychological testing and amyloid PET imaging, respectively. The use of amyloid PET in clinical practice is only indicated in patients with substantial diagnostic uncertainty due to atypical clinical presentation, multiple comorbidities and/or early age of onset. The relationship between amyloid-beta and cognition has been previously investigated, but no study has examined how neuropsychological features relate to the presence of amyloid pathology in the clinical population that meets the appropriate use criteria for amyloid PET imaging. In this study, we evaluated a clinical cohort of patients (
Identifiants
pubmed: 34222867
doi: 10.1093/braincomms/fcab035
pii: fcab035
pmc: PMC8244634
doi:
Types de publication
Journal Article
Langues
eng
Pagination
fcab035Subventions
Organisme : Medical Research Council
ID : MR/T033371/1
Pays : United Kingdom
Informations de copyright
© The Author(s) (2021). Published by Oxford University Press on behalf of the Guarantors of Brain.
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