DNA on drugs! A preliminary investigation of DNA deposition during the handling of illicit drug capsules.

DNA profiling from capsules and tablets offers a complementary tool to that of chemical profiling when investigating the manufacture and trade in illicit drugs. By sampling the outside of capsules, individuals who may have handled them during production, assembly or distribution may have deposited their DNA and can be identified if matched to a nominated profile or one on a relevant DNA database. The profiles can also be compared to those found on other capsules to potentially link various drug seizures. This study sampled the exterior of capsules after they had been handled in a controlled scenario to determine if informative DNA profiles could be generated from this brief contact. Two individuals of intermediate shedder status washed their hands and waited for 30 min before handling ten gelatine, vegetable, and enteric vegetable capsules each (n = 60). Contact was made for 15 s. Each capsule was swabbed and DNA isolated. The amount of recovered human DNA was quantified and profiled using the Verifiler Plus DNA profiling kit. Profiles were generated from 82% (49/60) of capsules tested with LR values above 1 × 10

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