Amended Safety Assessment of Fatty Acyl Sarcosines and Sarcosinate Salts as Used in Cosmetics.


Journal

International journal of toxicology
ISSN: 1092-874X
Titre abrégé: Int J Toxicol
Pays: United States
ID NLM: 9708436

Informations de publication

Date de publication:
10 2021
Historique:
pubmed: 7 7 2021
medline: 27 1 2022
entrez: 6 7 2021
Statut: ppublish

Résumé

The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of 5 acyl sarcosines and 9 sarcosinate salts as used in cosmetics; all of these ingredients are reported to function in cosmetics as hair conditioning agents and most also can function as surfactants-cleansing agents. The ingredients reviewed in this assessment are composed of an amide comprising a fatty acyl residue and sarcosine and are either free acids or simple salts thereof. The Panel relied on relevant new data, including concentration of use, and considered data from the previous Panel report, such as the reaction of sarcosine with oxidizing materials possibly resulting in nitrosation and the formation of

Identifiants

pubmed: 34225481
doi: 10.1177/10915818211023881
doi:

Substances chimiques

Cosmetics 0
Irritants 0
Nitroso Compounds 0
Salts 0
Surface-Active Agents 0
Sarcosine Z711V88R5F

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

117S-133S

Auteurs

Monice M Fiume (MM)

Cosmetic Ingredient Review Senior Director.

Wilma F Bergfeld (WF)

Expert Panel for Cosmetic Ingredient Safety Member.

Donald V Belsito (DV)

Expert Panel for Cosmetic Ingredient Safety Member.

Ronald A Hill (RA)

Expert Panel for Cosmetic Ingredient Safety Former Member.

Curtis D Klaassen (CD)

Expert Panel for Cosmetic Ingredient Safety Member.

Daniel C Liebler (DC)

Expert Panel for Cosmetic Ingredient Safety Member.

James G Marks (JG)

Expert Panel for Cosmetic Ingredient Safety Former Member.

Ronald C Shank (RC)

Expert Panel for Cosmetic Ingredient Safety Member.

Thomas J Slaga (TJ)

Expert Panel for Cosmetic Ingredient Safety Member.

Paul W Snyder (PW)

Expert Panel for Cosmetic Ingredient Safety Member.

Lillian J Gill (LJ)

Cosmetic Ingredient Review Former Director.

Bart Heldreth (B)

Cosmetic Ingredient Review Executive Director.

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Classifications MeSH