Recent trends in biodegradable polyester nanomaterials for cancer therapy.

Antineoplastic Agents Drug Delivery Systems Excipients Nanoparticles Neoplasms / drug therapy Polyesters
Cancer therapy Clinical application Drug delivery Metal-free synthesis Polyester nanomaterials

Journal

Materials science & engineering. C, Materials for biological applications
ISSN: 1873-0191
Titre abrégé: Mater Sci Eng C Mater Biol Appl
Pays: Netherlands
ID NLM: 101484109

Informations de publication

Date de publication:
Aug 2021
Historique:
received: 24 07 2020
revised: 12 05 2021
accepted: 18 05 2021
entrez: 6 7 2021
pubmed: 7 7 2021
medline: 8 7 2021
Statut: ppublish

Résumé

Biodegradable polyester nanomaterials-based drug delivery vehicles (DDVs) have been largely used in most of the cancer treatments due to its high biological performance and wider applications. In several previous studies, various biodegradable and biocompatible polyester backbones were used which are poly(lactic acid) (PLA), poly(ε-caprolactone) (PCL), poly(propylene fumarate) (PPF), poly(lactic-co-glycolic acid) (PLGA), poly(propylene carbonate) (PPC), polyhydroxyalkanoates (PHA), and poly(butylene succinate) (PBS). These polyesters were fabricated into therapeutic nanoparticles that carry drug molecules to the target site during the cancer disease treatment. In this review, we elaborately discussed the chemical synthesis of different synthetic polyesters and their use as nanodrug carriers (NCs) in cancer treatment. Further, we highlighted in brief the recent developments of metal-free semi-aromatic polyester nanomaterials along with its role as cancer drug delivery vehicles.

Identifiants

DOI: 10.1016/j.msec.2021.112198 PMID: 34225851
pubmed: 34225851
pii: S0928-4931(21)00338-6
doi: 10.1016/j.msec.2021.112198
pii:
doi:

Substances chimiques

Antineoplastic Agents 0
Excipients 0
Polyesters 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

112198

Informations de copyright

Copyright © 2021 Elsevier B.V. All rights reserved.

Auteurs

Piyush Kumar Gupta (PK)

Department of Life Sciences, School of Basic Sciences and Research, Sharda University, , Plot no. 32 - 34, Knowledge Park III, Greater Noida-201310, Uttar Pradesh, , India. Electronic address: piyush.kumar1@sharda.ac.in.

Rekha Gahtori (R)

Department of Biotechnology, Bhimtal Campus, Kumaun University, Nainital 263136, Uttarakhand, India.

Kavitha Govarthanan (K)

Department of Biotechnology, Bhupat Jyoti Mehta School of Biosciences, Indian Institute of Technology Madras, Chennai 600036, Tamilnadu, India.

Vineeta Sharma (V)

Department of Biotechnology, Bhupat Jyoti Mehta School of Biosciences, Indian Institute of Technology Madras, Chennai 600036, Tamilnadu, India.

Sreenath Pappuru (S)

Wolfson Faculty of Chemical Engineering, Technion-Israel Institute of Technology, Haifa 3200003, Israel.

Soumya Pandit (S)

Department of Life Sciences, School of Basic Sciences and Research, Sharda University, , Plot no. 32 - 34, Knowledge Park III, Greater Noida-201310, Uttar Pradesh, , India.

Abhilasha Singh Mathuriya (AS)

Department of Life Sciences, School of Basic Sciences and Research, Sharda University, , Plot no. 32 - 34, Knowledge Park III, Greater Noida-201310, Uttar Pradesh, , India.

Sunny Dholpuria (S)

Department of Life Sciences, School of Basic Sciences and Research, Sharda University, , Plot no. 32 - 34, Knowledge Park III, Greater Noida-201310, Uttar Pradesh, , India.

Dillip Kumar Bishi (DK)

Department of Biotechnology, Rama Devi Women's University, Bhubaneswar 751022, Odisha, India. Electronic address: dillipkumarbishi@rdwu.ac.in.

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Antinéoplasiques › Recent trends in biodegradable polyester...
questionsmedicales.fr › Thérapeutique › Traitement médicamenteux › Systèmes de délivrance de médicaments › Recent trends in biodegradable polyester...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Excipients pharmaceutiques › Excipients › Recent trends in biodegradable polyester...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Nanostructures › Nanoparticules › Recent trends in biodegradable polyester...
questionsmedicales.fr › Tumeurs › Recent trends in biodegradable polyester...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Matériaux biomédicaux et dentaires › Polymères › Polyesters › Recent trends in biodegradable polyester...