Mild anemia as a single independent predictor of mortality in patients with COVID-19.
COVID‐19
RBC
anemia
haemoglobin
mortality
prognosis
Journal
EJHaem
ISSN: 2688-6146
Titre abrégé: EJHaem
Pays: United States
ID NLM: 101761942
Informations de publication
Date de publication:
Aug 2021
Aug 2021
Historique:
received:
03
12
2020
revised:
10
01
2021
accepted:
12
01
2021
pubmed:
7
7
2021
medline:
7
7
2021
entrez:
6
7
2021
Statut:
epublish
Résumé
The coronavirus disease 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has led to an unprecedented international health crisis. COVID-19 clinical presentations cover a wide range from asymptomatic to severe illness and death. Given the limited therapeutic resources and unexpected clinical features of the disease, readily accessible predictive biomarkers are urgently needed to improve patient care and management. We asked the degree to which anemia may influence the outcome of patients with COVID-19. To this end, we identified 3777 patients who were positively diagnosed with COVID-19 between March 1 and April 1 2020 in New York City. We evaluated 2,562 patients with available red blood cell, hemoglobin, and related laboratory values. Multivariable cox proportional hazards regression showed that anemia was a significant independent predictor of mortality (hazard ratio (HR): 1.26, 95% Confidence Interval [CI]: 1.06-1.51), independent of age, sex, and comorbidities. There was a direct correlation between the degree of anemia and the risk of mortality when hemoglobin was treated as a continuous variable (HR
Identifiants
pubmed: 34226904
doi: 10.1002/jha2.167
pii: JHA2167
pmc: PMC8242891
doi:
Types de publication
Journal Article
Langues
eng
Pagination
319-326Subventions
Organisme : NCI NIH HHS
ID : R01 CA205975
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL136255
Pays : United States
Informations de copyright
© 2021 The Authors. eJHaem published by British Society for Haematology and John Wiley & Sons Ltd.
Déclaration de conflit d'intérêts
The authors declare no relevant conflict of interest
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