Assessing spatial distribution of COVID-19 prevalence in Brazil using decentralised sewage monitoring.
Covid-19
Decentralised sewage monitoring
Health vulnerability
Hotspots
Wastewater-based epidemiology
prevalence
Journal
Water research
ISSN: 1879-2448
Titre abrégé: Water Res
Pays: England
ID NLM: 0105072
Informations de publication
Date de publication:
01 Sep 2021
01 Sep 2021
Historique:
received:
04
12
2020
revised:
18
06
2021
accepted:
21
06
2021
pubmed:
7
7
2021
medline:
7
9
2021
entrez:
6
7
2021
Statut:
ppublish
Résumé
Brazil has become one of the epicentres of the COVID-19 pandemic, with cases heavily concentrated in large cities. Testing data is extremely limited and unreliable, which restricts health authorities' ability to deal with the pandemic. Given the stark demographic, social and economic heterogeneities within Brazilian cities, it is important to identify hotspots so that the limited resources available can have the greatest impact. This study shows that decentralised monitoring of SARS-CoV-2 RNA in sewage can be used to assess the distribution of COVID-19 prevalence in the city. The methodology developed in this study allowed the identification of hotspots by comprehensively monitoring sewers distributed through Belo Horizonte, Brazil's third largest city. Our results show that the most vulnerable neighbourhoods in the city were the hardest hit by the pandemic, indicating that, for many Brazilians, the situation is much worse than reported by official figures.
Identifiants
pubmed: 34229195
pii: S0043-1354(21)00586-8
doi: 10.1016/j.watres.2021.117388
pmc: PMC8666095
pii:
doi:
Substances chimiques
RNA, Viral
0
Sewage
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
117388Informations de copyright
Copyright © 2021 Elsevier Ltd. All rights reserved.
Références
Clin Chem. 2009 Apr;55(4):611-22
pubmed: 19246619
Environ Res. 2020 Dec;191:110092
pubmed: 32861728
Rev Bras Epidemiol. 2021 Jun 30;24:e210025
pubmed: 34231827
Nature. 2020 May;581(7809):465-469
pubmed: 32235945
Water Res. 2014 Nov 15;65:257-70
pubmed: 25129566
JAMA Netw Open. 2020 Jul 1;3(7):e2016938
pubmed: 32721027
Sci Total Environ. 2020 Sep 20;736:139652
pubmed: 32464333
Sci Total Environ. 2020 Aug 1;728:138764
pubmed: 32387778
BMJ. 2020 Apr 21;369:m1443
pubmed: 32317267
Nat Biotechnol. 2020 Oct;38(10):1164-1167
pubmed: 32948856
JAMA. 2020 Jun 2;323(21):2192-2195
pubmed: 32347898
J Hazard Mater. 2017 Feb 5;323(Pt A):156-165
pubmed: 27321747
Appl Environ Microbiol. 2015 Mar;81(6):2042-9
pubmed: 25576614
Emerg Infect Dis. 2020 Aug;26(8):
pubmed: 32396505
Water Res. 2020 Aug 15;181:115942
pubmed: 32425251
Epidemiol Infect. 2012 Jan;140(1):1-13
pubmed: 21849095
Environ Sci Technol. 2016 Jul 5;50(13):6803-13
pubmed: 26992352
Ann Intern Med. 2021 Jul;174(7):1012-1013
pubmed: 33780292
Ann Intern Med. 2021 Jul;174(7):936-944
pubmed: 33780289
Environ Int. 2020 Jun;139:105689
pubmed: 32283358
JAMA. 2020 May 12;323(18):1843-1844
pubmed: 32159775