Pituitary society expert Delphi consensus: operative workflow in endoscopic transsphenoidal pituitary adenoma resection.

Consensus Delphi Endoscopic endonasal Endoscopic transsphenoidal surgery Pituitary Pituitary adenoma Skull base surgery

Journal

Pituitary
ISSN: 1573-7403
Titre abrégé: Pituitary
Pays: United States
ID NLM: 9814578

Informations de publication

Date de publication:
Dec 2021
Historique:
accepted: 09 06 2021
pubmed: 8 7 2021
medline: 18 1 2022
entrez: 7 7 2021
Statut: ppublish

Résumé

Surgical workflow analysis seeks to systematically break down operations into hierarchal components. It facilitates education, training, and understanding of surgical variations. There are known educational demands and variations in surgical practice in endoscopic transsphenoidal approaches to pituitary adenomas. Through an iterative consensus process, we generated a surgical workflow reflective of contemporary surgical practice. A mixed-methods consensus process composed of a literature review and iterative Delphi surveys was carried out within the Pituitary Society. Each round of the survey was repeated until data saturation and > 90% consensus was reached. There was a 100% response rate and no attrition across both Delphi rounds. Eighteen international expert panel members participated. An extensive workflow of 4 phases (nasal, sphenoid, sellar and closure) and 40 steps, with associated technical errors and adverse events, were agreed upon by 100% of panel members across rounds. Both core and case-specific or surgeon-specific variations in operative steps were captured. Through an international expert panel consensus, a workflow for the performance of endoscopic transsphenoidal pituitary adenoma resection has been generated. This workflow captures a wide range of contemporary operative practice. The agreed "core" steps will serve as a foundation for education, training, assessment and technological development (e.g. models and simulators). The "optional" steps highlight areas of heterogeneity of practice that will benefit from further research (e.g. methods of skull base repair). Further adjustments could be made to increase applicability around the world.

Identifiants

pubmed: 34231079
doi: 10.1007/s11102-021-01162-3
pii: 10.1007/s11102-021-01162-3
pmc: PMC8259776
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

839-853

Subventions

Organisme : Wellcome Trust
Pays : United Kingdom

Informations de copyright

© 2021. The Author(s).

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Auteurs

Hani J Marcus (HJ)

Division of Neurosurgery, National Hospital for Neurology and Neurosurgery, London, UK. hani.marcus@ucl.ac.uk.
Wellcome/EPSRC Centre for Interventional and Surgical Sciences, University College London, London, UK. hani.marcus@ucl.ac.uk.

Danyal Z Khan (DZ)

Division of Neurosurgery, National Hospital for Neurology and Neurosurgery, London, UK.
Wellcome/EPSRC Centre for Interventional and Surgical Sciences, University College London, London, UK.

Anouk Borg (A)

Department of Neurosurgery, John Radcliffe Hospital, Oxford, UK.

Michael Buchfelder (M)

Department of Neurosurgery, University Hospital Erlangen, Erlangen, Germany.

Justin S Cetas (JS)

Department of Neurosurgery, Oregon Health & Science University, Portland, USA.

Justin W Collins (JW)

Department of Uro-Oncology, University College London Hospitals NHS Foundation Trust, London, UK.

Neil L Dorward (NL)

Division of Neurosurgery, National Hospital for Neurology and Neurosurgery, London, UK.

Maria Fleseriu (M)

Department of Neurosurgery, Oregon Health & Science University, Portland, USA.
Departments of Medicine (Endocrinology), Oregon Health & Science University, Portland, USA.

Mark Gurnell (M)

Division of Clinical Endocrinology & NIHR Cambridge Biomedical Research Centre, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Wellcome Trust-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, UK.

Mohsen Javadpour (M)

Department of Neurosurgery, National Neurosurgical Centre, Beaumont Hospital, Dublin, Ireland.

Pamela S Jones (PS)

Department of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, USA.

Chan Hee Koh (CH)

Division of Neurosurgery, National Hospital for Neurology and Neurosurgery, London, UK.
Wellcome/EPSRC Centre for Interventional and Surgical Sciences, University College London, London, UK.

Hugo Layard Horsfall (H)

Division of Neurosurgery, National Hospital for Neurology and Neurosurgery, London, UK.
Wellcome/EPSRC Centre for Interventional and Surgical Sciences, University College London, London, UK.

Adam N Mamelak (AN)

Department of Neurosurgery and Pituitary Center, Cedars-Sinai Medical Center, Los Angeles, USA.

Pietro Mortini (P)

Department of Neurosurgery, San Raffaele University Health Institute Milan, Milan, Italy.

William Muirhead (W)

Division of Neurosurgery, National Hospital for Neurology and Neurosurgery, London, UK.
Wellcome/EPSRC Centre for Interventional and Surgical Sciences, University College London, London, UK.

Nelson M Oyesiku (NM)

Department of Neurosurgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Department of Medicine (Endocrinology), University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

Theodore H Schwartz (TH)

Department of Neurosurgery, Weill Medical College of Cornell University, New York, USA.

Saurabh Sinha (S)

Department of Neurosurgery, Royal Hallamshire Hospital & Sheffield Children's Hospital, Sheffield, UK.

Danail Stoyanov (D)

Wellcome/EPSRC Centre for Interventional and Surgical Sciences, University College London, London, UK.

Luis V Syro (LV)

Department of Neurosurgery, Hospital Pablo Tobon Uribe and Clinica Medellin-Grupo Quirónsalud, Medellin, Colombia.

Georgios Tsermoulas (G)

Department of Neurosurgery, Queen Elizabeth Hospital Birmingham, Birmingham, UK.
Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK.

Adam Williams (A)

Department of Neurosurgery, Southmead Hospital Bristol, Bristol, UK.

Mark J Winder (MJ)

Department of Neurosurgery, St Vincent's Public and Private Hospitals, Sydney, Australia.

Gabriel Zada (G)

Department of Neurosurgery, University of Southern California, Los Angeles, California, USA.

Edward R Laws (ER)

Department of Neurosurgery, Brigham and Women's Hospital, BTM 4, 60 Fenwood Road, Boston, USA.

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