GPR3 sets brown fat on fire.

Adipocytes, Brown Adipose Tissue, Brown / metabolism Humans Lipolysis Obesity / metabolism Receptors, G-Protein-Coupled / metabolism Thermogenesis

Journal

Cell metabolism
ISSN: 1932-7420
Titre abrégé: Cell Metab
Pays: United States
ID NLM: 101233170

Informations de publication

Date de publication:
06 07 2021
Historique:
entrez: 7 7 2021
pubmed: 8 7 2021
medline: 7 1 2022
Statut: ppublish

Résumé

Activation of thermogenic adipocytes, a process canonically driven by norepinephrine through β-adrenergic receptors, presents an appealing therapeutic approach to combat obesity. Recent work by Sveidahl Johansen et al., 2021 published in Cell has identified a noncanonical mechanism of brown adipocyte activation, in which lipolysis transcriptionally drives the constitutive activation of the G

Identifiants

DOI: 10.1016/j.cmet.2021.06.003 PMID: 34233169
pubmed: 34233169
pii: S1550-4131(21)00273-4
doi: 10.1016/j.cmet.2021.06.003
pii:
doi:

Substances chimiques

GPR3 protein, human 0
Receptors, G-Protein-Coupled 0

Types de publication

Journal Article Comment

Langues

eng

Sous-ensembles de citation

IM

Pagination

1271-1273

Commentaires et corrections

Type : CommentOn

Informations de copyright

Copyright © 2021 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of interests The authors declare no competing interests.

Auteurs

Miroslav Balaz (M)

Institute of Food, Nutrition and Health, ETH Zürich, Schwerzenbach, Switzerland; Institute of Experimental Endocrinology, Biomedical Research Center at the Slovak Academy of Sciences, Bratislava, Slovakia.

Christian Wolfrum (C)

Institute of Food, Nutrition and Health, ETH Zürich, Schwerzenbach, Switzerland. Electronic address: christian-wolfrum@ethz.ch.

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Classifications MeSH

questionsmedicales.fr › Cellules › Cellules du tissu conjonctif › Adipocytes › Adipocytes bruns › GPR3 sets brown fat on fire.
questionsmedicales.fr › Tissus › Tissu conjonctif › Tissu adipeux › Tissu adipeux brun › GPR3 sets brown fat on fire.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › GPR3 sets brown fat on fire.
questionsmedicales.fr › Métabolisme › Métabolisme lipidique › Lipolyse › GPR3 sets brown fat on fire.
questionsmedicales.fr › États, signes et symptômes pathologiques › Signes et symptômes › Obésité › GPR3 sets brown fat on fire.
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs couplés aux protéines G › GPR3 sets brown fat on fire.
questionsmedicales.fr › Phénomènes biologiques › Adaptation biologique › Adaptation physiologique › Régulation de la température corporelle › Thermogenèse › GPR3 sets brown fat on fire.