Renal Effects of Hyperbaric Oxygen Therapy in Patients with Diabetes Mellitus: A Retrospective Study.


Journal

International journal of nephrology
ISSN: 2090-214X
Titre abrégé: Int J Nephrol
Pays: United States
ID NLM: 101546753

Informations de publication

Date de publication:
2021
Historique:
received: 31 03 2021
revised: 21 05 2021
accepted: 28 05 2021
entrez: 8 7 2021
pubmed: 9 7 2021
medline: 9 7 2021
Statut: epublish

Résumé

Hyperbaric oxygen therapy (HBOT) is an adjunctive treatment for patients with diabetic foot ulcers. The prolonged high oxygen level used in HBOT can produce oxidative stress, which may be harmful to the kidney. Animal experiments suggest HBOT does not harm renal function and may have an antiproteinuric effect, but little is known on the effect of HBOT in humans. We performed a retrospective chart review of 94 patients with diabetes mellitus who underwent HBOT at our institution over an eight-year period. Thirty-two patients had serum creatinine levels within 60 days of the start and the end of treatment. Creatinine levels were 1.41 ± 0.89 mg/dl before and 1.52 ± 1.17 mg/dl after hyperbaric treatments with no statistically significant difference (mean (postcreatinine + precreatinine/2) = 0.10 mg/dl, SE = 0.11,

Identifiants

pubmed: 34234965
doi: 10.1155/2021/9992352
pmc: PMC8216821
doi:

Types de publication

Journal Article

Langues

eng

Pagination

9992352

Informations de copyright

Copyright © 2021 Martin Sedlacek et al.

Déclaration de conflit d'intérêts

The authors declare that they have no conflicts of interest.

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Auteurs

Martin Sedlacek (M)

Section of Nephrology, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03756, USA.

Nicole P Harlan (NP)

Section of Hyperbaric Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03756, USA.

Jay C Buckey (JC)

Geisel School of Medicine, Section Chief, Section of Hyperbaric Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03756, USA.

Classifications MeSH