Health-related quality of life among colorectal cancer survivors of diverse sexual orientations.
cancer survivorship
colorectal neoplasms
quality of life
sexual and gender minorities
Journal
Cancer
ISSN: 1097-0142
Titre abrégé: Cancer
Pays: United States
ID NLM: 0374236
Informations de publication
Date de publication:
15 10 2021
15 10 2021
Historique:
revised:
18
05
2021
received:
02
03
2021
accepted:
19
05
2021
pubmed:
9
7
2021
medline:
11
3
2022
entrez:
8
7
2021
Statut:
ppublish
Résumé
The purpose of this study was to examine the health-related quality of life of sexual minority survivors in comparison with heterosexual survivors. Four hundred eighty eligible survivors participated in a telephone survey that measured survivors' outcomes, which consisted of physical and mental quality of life and self-rated fair or poor health. These survivors were diagnosed with stage I, II, or III colorectal cancer an average of 3 years before the survey and were recruited from 4 cancer registries. Using forward selection with generalized linear models or logistic regression models, the authors considered 4 domains-personal factors, environmental factors, health condition characteristics, and body function and structure-as correlates for each survivorship outcome. The authors found that unadjusted physical quality of life and self-rated fair/poor health were similar for all survivors. Sexual minority survivors had poorer unadjusted mental quality of life in comparison with heterosexual survivors. After adjustments for covariates, this difference was no longer statistically significant. Three domains (personal factors, health condition characteristics, and body function and structure) explained colorectal cancer survivors' fair/poor health and 46% of the variance in physical quality of life, whereas 56% of the variance in mental quality of life was explained by personal factors, body function and structure, and environmental factors. This study has identified modifiable factors that can be used to improve cancer survivors' quality of life and are, therefore, relevant to ongoing efforts to improve the survivorship experience.
Sections du résumé
BACKGROUND
The purpose of this study was to examine the health-related quality of life of sexual minority survivors in comparison with heterosexual survivors.
METHODS
Four hundred eighty eligible survivors participated in a telephone survey that measured survivors' outcomes, which consisted of physical and mental quality of life and self-rated fair or poor health. These survivors were diagnosed with stage I, II, or III colorectal cancer an average of 3 years before the survey and were recruited from 4 cancer registries. Using forward selection with generalized linear models or logistic regression models, the authors considered 4 domains-personal factors, environmental factors, health condition characteristics, and body function and structure-as correlates for each survivorship outcome.
RESULTS
The authors found that unadjusted physical quality of life and self-rated fair/poor health were similar for all survivors. Sexual minority survivors had poorer unadjusted mental quality of life in comparison with heterosexual survivors. After adjustments for covariates, this difference was no longer statistically significant. Three domains (personal factors, health condition characteristics, and body function and structure) explained colorectal cancer survivors' fair/poor health and 46% of the variance in physical quality of life, whereas 56% of the variance in mental quality of life was explained by personal factors, body function and structure, and environmental factors.
CONCLUSIONS
This study has identified modifiable factors that can be used to improve cancer survivors' quality of life and are, therefore, relevant to ongoing efforts to improve the survivorship experience.
Identifiants
pubmed: 34237147
doi: 10.1002/cncr.33762
pmc: PMC8478814
mid: NIHMS1712751
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
3847-3855Subventions
Organisme : NCI NIH HHS
ID : R01 CA181392
Pays : United States
Organisme : National Cancer Institute at the National Institutes of Health
ID : 1R01CA181392-01A1
Informations de copyright
© 2021 American Cancer Society.
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