Structural and functional insights into human tRNA guanine transgylcosylase.


Journal

RNA biology
ISSN: 1555-8584
Titre abrégé: RNA Biol
Pays: United States
ID NLM: 101235328

Informations de publication

Date de publication:
15 10 2021
Historique:
pubmed: 10 7 2021
medline: 26 2 2022
entrez: 9 7 2021
Statut: ppublish

Résumé

The eukaryotic tRNA guanine transglycosylase (TGT) is an RNA modifying enzyme incorporating queuine, a hypermodified guanine derivative, into the tRNAs

Identifiants

pubmed: 34241577
doi: 10.1080/15476286.2021.1950980
pmc: PMC8677009
doi:

Substances chimiques

Guanine 5Z93L87A1R
RNA, Transfer 9014-25-9
Pentosyltransferases EC 2.4.2.-
queuine tRNA-ribosyltransferase EC 2.4.2.29

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

382-396

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Auteurs

Katharina Sievers (K)

Department of Molecular Structural Biology, University of Göttingen, Göttingen, Germany.

Luisa Welp (L)

Bioanalytical Mass Spectrometry Group, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany.

Henning Urlaub (H)

Bioanalytical Mass Spectrometry Group, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany.
Bioanalytics Group, Institute for Clinical Chemistry, University Medical Center Göttingen, Göttingen, Germany.

Ralf Ficner (R)

Department of Molecular Structural Biology, University of Göttingen, Göttingen, Germany.
Cluster of Excellence "Multiscale Bioimaging: From Molecular Machines to Networks of Excitable Cells" (Mbexc), University of Göttingen, Göttingen, Germany.

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Classifications MeSH