Time scale performance of rapid antigen testing for SARS-CoV-2: Evaluation of 10 rapid antigen assays.
COVID-19 diagnosis
SARS-CoV-2
rapid antigen tests
surveillance
Journal
Journal of medical virology
ISSN: 1096-9071
Titre abrégé: J Med Virol
Pays: United States
ID NLM: 7705876
Informations de publication
Date de publication:
12 2021
12 2021
Historique:
revised:
29
06
2021
received:
02
06
2021
accepted:
06
07
2021
pubmed:
10
7
2021
medline:
28
10
2021
entrez:
9
7
2021
Statut:
ppublish
Résumé
There is a great demand for more rapid tests for SARS-CoV-2 detection to reduce waiting time, boost public health strategies for combating disease, decrease costs, and prevent overwhelming laboratory capacities. This study was conducted to assess the performance of 10 lateral flow device viral antigen immunoassays for the detection of SARS-CoV-2 in nasopharyngeal swab specimens. We analyzed 231 nasopharyngeal samples collected from October 2020 to December 2020, from suspected COVID-19 cases and contacts of positive cases at Biotechnology Research Center laboratories, Tripoli, Libya. The performance of 10 COVID-19 Antigen (Ag) rapid test devices for the detection of SARS-CoV-2 antigen was compared to a quantitative reverse transcription-polymerase chain reaction (RT-qPCR). In this study, 161 cases had symptoms consistent with COVID-19. The mean duration from symptom onset was 6.6 ± 4.3 days. The median cycle threshold (C
Identifiants
pubmed: 34241912
doi: 10.1002/jmv.27186
pmc: PMC8426927
doi:
Substances chimiques
Antigens, Viral
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
6512-6518Informations de copyright
© 2021 Wiley Periodicals LLC.
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