In-field Evaluation of SD Bioline HBsAg Whole Blood Rapid Test in Pregnant Women in Cambodia: the ANRS 12345 TA PROHM Study.
Adult
Female
Hepatitis B
/ blood
Hepatitis B Surface Antigens
/ blood
Hepatitis B virus
/ immunology
Humans
Infectious Disease Transmission, Vertical
/ prevention & control
Pregnancy
Pregnancy Complications, Infectious
/ blood
Pregnant Women
Prospective Studies
Reagent Kits, Diagnostic
Reproducibility of Results
Sensitivity and Specificity
Young Adult
Cambodia
Hepatitis B Virus
Mother-to-child transmission
Pregnant women
Rapid diagnosis tests
Journal
Diagnostic microbiology and infectious disease
ISSN: 1879-0070
Titre abrégé: Diagn Microbiol Infect Dis
Pays: United States
ID NLM: 8305899
Informations de publication
Date de publication:
Oct 2021
Oct 2021
Historique:
received:
12
02
2021
revised:
04
06
2021
accepted:
06
06
2021
pubmed:
10
7
2021
medline:
3
11
2021
entrez:
9
7
2021
Statut:
ppublish
Résumé
The objective is to assess the in-field performance of HBsAg whole blood rapid diagnosis test (RDT) as compared to plasmatic HBsAg RDT to diagnose HBV infection among pregnant women in Cambodia. Blood was collected on EDTA tubes from pregnant woman screened for the TA PROHM - ANRS 12345 study. Whole blood HBsAg RDT results were crossed compared with the plasmatic HBsAg RDT results, which was defined for this study as the gold standard. From December 2018 to May 2019, 4997 pregnant women were screened. The median age was 27.2 years old, 14% were screened in Phnom Penh and 86% in Siem Reap. Whole blood HBsAg RDT perform excellently with a sensitivity of 100% (95% CI, 98.7 - 100) and specificity of 100% (95% CI, 99.9 - 100). Whole blood HBs Ag RDT is as accurate as plasmatic one and could be used in remote areas.
Identifiants
pubmed: 34243135
pii: S0732-8893(21)00145-0
doi: 10.1016/j.diagmicrobio.2021.115452
pii:
doi:
Substances chimiques
Hepatitis B Surface Antigens
0
Reagent Kits, Diagnostic
0
Types de publication
Case Reports
Multicenter Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
115452Informations de copyright
Copyright © 2021 Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing interest All the authors do not have an association that might pose a conflict of interest.