Prevalence of exercise-induced oxygen desaturation after recovery from SARS-CoV-2 pneumonia and use of lung ultrasound to predict need for pulmonary rehabilitation.

6-min walking test Acute respiratory failure COVID-19 Pneumonia Lung ultrasound desaturation

Journal

Pulmonology
ISSN: 2531-0437
Titre abrégé: Pulmonology
Pays: Spain
ID NLM: 101723786

Informations de publication

Date de publication:
Dec 2023
Historique:
received: 11 02 2021
revised: 14 05 2021
accepted: 17 05 2021
pubmed: 13 7 2021
medline: 13 7 2021
entrez: 12 7 2021
Statut: ppublish

Résumé

Persistence of breathlessness after recovery from SARS-CoV-2 pneumonia is frequent. Recovery from acute respiratory failure (ARF) is usually determined by normalized arterial blood gases (ABGs), but the prevalence of persistent exercise-induced desaturation (EID) and dyspnea is still unknown. We investigated the prevalence of EID in 70 patients with normal arterial oxygen at rest after recovery from ARF due to COVID-19 pneumonia. Patients underwent a 6-min walking test (6MWT) before discharge from hospital. We recorded dyspnea score and heart rate during 6MWT. We also investigated the possible role of lung ultrasound (LU) in predicting EID. Patients underwent a LU scan and scores for each explored area were summed to give a total LU score. In 30 patients (43%), oxygen desaturation was >4% during 6MWT. These patients had significantly higher dyspnea and heart rate compared to non-desaturators. LU score >8.5 was significantly able to discriminate patients with EID. In SARS-CoV-2 pneumonia, ABGs at discharge cannot predict the persistence of EID, which is frequent. LU may be useful to identify patients at risk who could benefit from a rehabilitation program.

Sections du résumé

BACKGROUND BACKGROUND
Persistence of breathlessness after recovery from SARS-CoV-2 pneumonia is frequent. Recovery from acute respiratory failure (ARF) is usually determined by normalized arterial blood gases (ABGs), but the prevalence of persistent exercise-induced desaturation (EID) and dyspnea is still unknown.
METHODS METHODS
We investigated the prevalence of EID in 70 patients with normal arterial oxygen at rest after recovery from ARF due to COVID-19 pneumonia. Patients underwent a 6-min walking test (6MWT) before discharge from hospital. We recorded dyspnea score and heart rate during 6MWT. We also investigated the possible role of lung ultrasound (LU) in predicting EID. Patients underwent a LU scan and scores for each explored area were summed to give a total LU score.
RESULTS RESULTS
In 30 patients (43%), oxygen desaturation was >4% during 6MWT. These patients had significantly higher dyspnea and heart rate compared to non-desaturators. LU score >8.5 was significantly able to discriminate patients with EID.
CONCLUSION CONCLUSIONS
In SARS-CoV-2 pneumonia, ABGs at discharge cannot predict the persistence of EID, which is frequent. LU may be useful to identify patients at risk who could benefit from a rehabilitation program.

Identifiants

pubmed: 34247995
pii: S2531-0437(21)00117-3
doi: 10.1016/j.pulmoe.2021.05.008
pmc: PMC8175480
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

S4-S8

Informations de copyright

Copyright © 2021 Sociedade Portuguesa de Pneumologia. Published by Elsevier España, S.L.U. All rights reserved.

Déclaration de conflit d'intérêts

Conflicts of interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

A Carlucci (A)

U.O. Pneumologia Riabilitativa, IRCCS Istituti Clinici Scientifici Salvatore Maugeri, Pavia, Italy; Dipartimento di Medicina e Chirurgia, Università Insubria-Varese e Como, Italy. Electronic address: annalisa.carlucci@icsmaugeri.it.

M Paneroni (M)

U.O. Pneumologia Riabilitativa, IRCCS Istituti Clinici Scientifici Salvatore Maugeri, Lumezzane (Brescia), Italy.

M Carotenuto (M)

U.O. Pneumologia Riabilitativa, IRCCS Istituti Clinici Scientifici Salvatore Maugeri, Pavia, Italy.

E Bertella (E)

U.O. Pneumologia Riabilitativa, IRCCS Istituti Clinici Scientifici Salvatore Maugeri, Lumezzane (Brescia), Italy.

S Cirio (S)

U.O. Pneumologia Riabilitativa, IRCCS Istituti Clinici Scientifici Salvatore Maugeri, Pavia, Italy.

A Gandolfo (A)

U.O. Pneumologia Riabilitativa, IRCCS Istituti Clinici Scientifici Salvatore Maugeri, Pavia, Italy.

C Simonelli (C)

U.O. Pneumologia Riabilitativa, IRCCS Istituti Clinici Scientifici Salvatore Maugeri, Lumezzane (Brescia), Italy.

M Vigna (M)

U.O. Pneumologia Riabilitativa, IRCCS Istituti Clinici Scientifici Salvatore Maugeri, Pavia, Italy.

C Lastoria (C)

U.O. Pneumologia Riabilitativa, IRCCS Istituti Clinici Scientifici Salvatore Maugeri, Pavia, Italy.

A Malovini (A)

Laboratorio di Informatica e Sistemistica per la Ricerca Clinica, IRCCS Istituti Clinici Scientifici Salvatore Maugeri, Pavia, Italy.

B Fusar Poli (B)

U.O. Pneumologia Riabilitativa, IRCCS Istituti Clinici Scientifici Salvatore Maugeri, Pavia, Italy.

M Vitacca (M)

U.O. Pneumologia Riabilitativa, IRCCS Istituti Clinici Scientifici Salvatore Maugeri, Lumezzane (Brescia), Italy.

Classifications MeSH