Comparative Analysis of Emerging B.1.1.7+E484K SARS-CoV-2 Isolates.
B.1.1.7+E484K
convergent
escape mutation
vaccine
variant of concern
Journal
Open forum infectious diseases
ISSN: 2328-8957
Titre abrégé: Open Forum Infect Dis
Pays: United States
ID NLM: 101637045
Informations de publication
Date de publication:
Jul 2021
Jul 2021
Historique:
received:
25
04
2021
accepted:
03
06
2021
entrez:
13
7
2021
pubmed:
14
7
2021
medline:
14
7
2021
Statut:
epublish
Résumé
We report the genome of a B.1.1.7+E484K severe acute respiratory syndrome coronavirus 2 from Southeastern Pennsylvania and compare it with all high-coverage B.1.1.7+E484K genomes (n = 235) available. Analyses showed the existence of at least 4 distinct clades of this variant circulating in the United States and the possibility of at least 59 independent acquisitions of the E484K mutation.
Identifiants
pubmed: 34254040
doi: 10.1093/ofid/ofab300
pii: ofab300
pmc: PMC8244812
doi:
Types de publication
Journal Article
Langues
eng
Pagination
ofab300Subventions
Organisme : NICHD NIH HHS
ID : R61 HD105594
Pays : United States
Commentaires et corrections
Type : UpdateOf
Informations de copyright
© The Author(s) 2021. Published by Oxford University Press on behalf of Infectious Diseases Society of America.
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