Conjugated Hyperbilirubinemia in Infants: Is There Still a Role for ERCP?


Journal

Canadian journal of gastroenterology & hepatology
ISSN: 2291-2797
Titre abrégé: Can J Gastroenterol Hepatol
Pays: Egypt
ID NLM: 101623613

Informations de publication

Date de publication:
2021
Historique:
received: 31 03 2021
accepted: 17 06 2021
entrez: 14 7 2021
pubmed: 15 7 2021
medline: 21 10 2021
Statut: epublish

Résumé

Over a twenty-year period, we performed 255 ERCP procedures in infants aged up to 1 year. ERCP was indicated in cholestatic infants with suspicion of biliary obstruction. The most common diagnosis was biliary atresia (48%), choledochal cysts (13%), and choledocholithiasis (4%). The procedure complication rate was 13.7%. Hyperamylasemia occurred in 12.9%. More severe complications were rare-0.8% of ERCP procedure. There were no cases of postprocedural pancreatitis or death. Our study has proved that ERCP is a safe and reliable method in this age group. Its high specificity and negative predictive value for extrahepatic biliary atresia can prevent unnecessary surgeries in patients with normal bile ducts or endoscopically treatable pathologies.

Identifiants

pubmed: 34258256
doi: 10.1155/2021/9969825
pmc: PMC8249117
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

9969825

Informations de copyright

Copyright © 2021 Jan Stovicek et al.

Déclaration de conflit d'intérêts

The authors declare that they have no conflicts of interest.

Références

Future Sci OA. 2020 Mar 17;6(5):FSO466
pubmed: 32518681
World J Surg. 2017 Oct;41(10):2631-2637
pubmed: 28589237
World J Pediatr. 2016 Feb;12(1):35-43
pubmed: 26684313
J Pediatr. 2015 Apr;166(4):897-902.e1
pubmed: 25681196
Am J Surg. 1977 Aug;134(2):263-9
pubmed: 889044
J Pediatr Gastroenterol Nutr. 2019 Jan;68(1):64-67
pubmed: 30044307
Pediatrics. 2009 May;123(5):1280-6
pubmed: 19403492
PLoS One. 2019 Jan 17;14(1):e0210805
pubmed: 30653580
Gastrointest Endosc. 1991 Sep-Oct;37(5):522-6
pubmed: 1936828
Endoscopy. 2010 Feb;42(2):121-6
pubmed: 20140829
PLoS One. 2015 Jul 29;10(7):e0132270
pubmed: 26221719
J Pediatr Gastroenterol Nutr. 2004 Aug;39(2):115-28
pubmed: 15269615
Hepatology. 2008 Apr;47(4):1233-40
pubmed: 18306391
J Pediatr Gastroenterol Nutr. 2000 Oct;31(4):411-7
pubmed: 11045839
Prz Gastroenterol. 2017;12(4):303-309
pubmed: 29359001
J Pediatr Gastroenterol Nutr. 2020 Aug;71(2):e54-e58
pubmed: 32304552

Auteurs

Jan Stovicek (J)

Department of Internal Medicine, Charles University in Prague, 2nd Faculty of Medicine, University Hospital Motol in Prague, Prague, Czech Republic.

Stepan Hlava (S)

Department of Internal Medicine, Charles University in Prague, 2nd Faculty of Medicine, University Hospital Motol in Prague, Prague, Czech Republic.

Radan Keil (R)

Department of Internal Medicine, Charles University in Prague, 2nd Faculty of Medicine, University Hospital Motol in Prague, Prague, Czech Republic.

Jiri Drabek (J)

Department of Internal Medicine, Charles University in Prague, 2nd Faculty of Medicine, University Hospital Motol in Prague, Prague, Czech Republic.

Jindra Lochmannova (J)

Department of Internal Medicine, Charles University in Prague, 2nd Faculty of Medicine, University Hospital Motol in Prague, Prague, Czech Republic.

Petra Koptová (P)

Department of Internal Medicine, Charles University in Prague, 2nd Faculty of Medicine, University Hospital Motol in Prague, Prague, Czech Republic.

Martin Wasserbauer (M)

Department of Internal Medicine, Charles University in Prague, 2nd Faculty of Medicine, University Hospital Motol in Prague, Prague, Czech Republic.

Barbora Frybova (B)

Department of Pediatric Surgery, Charles University in Prague, 2nd Faculty of Medicine, University Hospital Motol in Prague, Prague, Czech Republic.

Jiri Snajdauf (J)

Department of Pediatric Surgery, Charles University in Prague, 2nd Faculty of Medicine, University Hospital Motol in Prague, Prague, Czech Republic.

Radana Kotalova (R)

Department of Pediatry, Charles University in Prague, 2nd Faculty of Medicine, University Hospital Motol in Prague, Prague, Czech Republic.

Michal Rygl (M)

Department of Pediatric Surgery, Charles University in Prague, 2nd Faculty of Medicine, University Hospital Motol in Prague, Prague, Czech Republic.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH