Refracture and mortality following hospitalization for severe osteoporotic fractures: The Fractos Study.

FRACTURE PREVENTION FRACTURE RISK ASSESSMENT GENERAL POPULATION STUDIES OSTEOPOROSIS THERAPEUTICS

Journal

JBMR plus
ISSN: 2473-4039
Titre abrégé: JBMR Plus
Pays: England
ID NLM: 101707013

Informations de publication

Date de publication:
Jul 2021
Historique:
received: 23 02 2021
revised: 16 04 2021
accepted: 20 04 2021
entrez: 14 7 2021
pubmed: 15 7 2021
medline: 15 7 2021
Statut: epublish

Résumé

Severe osteoporotic fractures (hip, proximal humerus, pelvic, vertebral and multiple rib fractures) carry an increased risk of mortality. This retrospective cohort study in the French national healthcare database aimed to estimate refracture and mortality rates after severe osteoporotic fractures at different sites, and to identify mortality-related variables. A total of 356,895 patients hospitalized for severe osteoporotic fracture between 2009 and 2014 inclusive were analyzed. The cohort was followed for 2 to 8 years up to the study end or until the patient died. Data were extracted on subsequent hospitalizations, refracture events, treatments, comorbidities of interest and survival. Time to refracture and survival were described using Kaplan-Meier analysis by site of fracture and overall. Mortality risk factors were identified using a Cox model. Hip fractures accounted for 60.4% of the sample (

Identifiants

pubmed: 34258503
doi: 10.1002/jbm4.10507
pii: JBM410507
pmc: PMC8260818
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e10507

Informations de copyright

© 2021 The Authors. JBMR Plus published by Wiley Periodicals LLC on behalf of American Society for Bone and Mineral Research.

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Auteurs

Christian Roux (C)

Department of Rheumatology Cochin Hospital, Assistance Publique - Hôpitaux de Paris Centre, Institut National de la Santé et de la Recherche Médicale (INSERM) Unités Mixtes de Recherche (UMR) 1153, Université de Paris Paris France.

Thierry Thomas (T)

Department of Rheumatology Hôpital Nord, Centre Hospitalier Universitaire (CHU) Saint-Etienne, INSERM U1059, Lyon University Saint-Etienne France.

Julien Paccou (J)

Department of Rheumatology Lille University, CHU Lille, Marrow Adiposity and Bone Laboratory (MABlab) ULR 4490 Lille France.

Geoffray Bizouard (G)

IQVIA Courbevoie France.

Anne Crochard (A)

UCB Pharma Colombes France.

Emese Toth (E)

UCB Pharma Colombes France.

Magali Lemaitre (M)

IQVIA Courbevoie France.

Frédérique Maurel (F)

IQVIA Courbevoie France.

Laure Perrin (L)

UCB Pharma Colombes France.

Florence Tubach (F)

Department of Public Health, Pharmacoepidemiology Center (Cephepi) Sorbonne University, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, AP-HP Sorbonne University, Pitié-Salpêtrière Hospital, CIC-1422 Paris France.

Classifications MeSH