Lost bones: differential diagnosis of acro-osteolysis seen by the pediatric rheumatologist.
Acro-osteolysis
Arthritis
Genetic disorders
Hyperparathyroidism
Ischemia
Neuropathy
Pediatrics
Radiographs
Systemic sclerosis
Trauma
Journal
Pediatric rheumatology online journal
ISSN: 1546-0096
Titre abrégé: Pediatr Rheumatol Online J
Pays: England
ID NLM: 101248897
Informations de publication
Date de publication:
14 Jul 2021
14 Jul 2021
Historique:
received:
03
02
2021
accepted:
12
04
2021
entrez:
15
7
2021
pubmed:
16
7
2021
medline:
14
1
2022
Statut:
epublish
Résumé
Acro-osteolysis is a radiographic finding which refers to bone resorption of the distal phalanges. Acro-osteolysis is associated with various conditions and its presence should prompt the clinician to search for the underlying etiology. The aim of this review is to discuss disorders with which acro-osteolysis is associated and their distinguishing features, with a focus on the pediatric population. A targeted literature review was performed using the term "acro-osteolysis" in combination with other key terms. The primary search results were supplemented using reference citations. Articles published prior to the year 2000 were included if they described additional associations not encountered in the more recent literature. Genetic disorders (particularly primary hypertrophic osteoarthropathy and skeletal dysplasias) and rheumatic diseases (particularly psoriatic arthritis and systemic sclerosis) are the most frequently encountered conditions associated with acro-osteolysis in children. Hyperparathyroidism, neuropathy, local trauma and thermal injury, and spinal dysraphism should also be included in the differential diagnosis. Although acro-osteolysis is uncommon, its presence should prompt the clinician to consider a differential diagnosis based on clinical and radiographic features.
Identifiants
pubmed: 34261502
doi: 10.1186/s12969-021-00596-0
pii: 10.1186/s12969-021-00596-0
pmc: PMC8278612
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
113Informations de copyright
© 2021. The Author(s).
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