3D-printed microchip electrophoresis device containing spiral electrodes for integrated capacitively coupled contactless conductivity detection.
3D printing
Liquid metal electrodes
Microchip electrophoresis
Journal
Analytical and bioanalytical chemistry
ISSN: 1618-2650
Titre abrégé: Anal Bioanal Chem
Pays: Germany
ID NLM: 101134327
Informations de publication
Date de publication:
Jan 2022
Jan 2022
Historique:
received:
18
03
2021
accepted:
21
06
2021
revised:
16
06
2021
pubmed:
16
7
2021
medline:
16
7
2021
entrez:
15
7
2021
Statut:
ppublish
Résumé
In this work, we demonstrate for the first time the design and fabrication of microchip electrophoresis devices containing cross-shaped channels and spiral electrodes around the separation channel for microchip electrophoresis and capacitively coupled contactless conductivity detection. The whole device was prepared in a digital light processing-based 3D printer in poly(ethylene glycol) diacrylate resin. Outstanding X-Y resolution of the customized 3D printer ensured the fabrication of 40-μm cross section channels. The spiral channels were filled with melted gallium to form conductive electrodes around the separation channel. We demonstrate the applicability of the device on the separation of sodium, potassium, and lithium cations by microchip electrophoresis. Graphical abstract.
Identifiants
pubmed: 34263346
doi: 10.1007/s00216-021-03494-2
pii: 10.1007/s00216-021-03494-2
pmc: PMC8748415
mid: NIHMS1762156
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
545-550Subventions
Organisme : Fundação de Amparo à Pesquisa do Estado de São Paulo
ID : 2018/06478-3
Organisme : NIBIB NIH HHS
ID : R01 EB027096
Pays : United States
Organisme : Conselho Nacional de Desenvolvimento Científico e Tecnológico
ID : 465389/2014-7
Organisme : NIGMS NIH HHS
ID : R15 GM123405
Pays : United States
Organisme : NIH HHS
ID : R15GM123405
Pays : United States
Informations de copyright
© 2021. Springer-Verlag GmbH Germany, part of Springer Nature.
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