Spontaneous versus morcellator-related benign metastasizing leiomyoma-A retrospective study.
benign metastasizing leiomyoma
endoscopic surgery
laparoscopy
morbidity
surgical technique
Journal
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
ISSN: 1879-3479
Titre abrégé: Int J Gynaecol Obstet
Pays: United States
ID NLM: 0210174
Informations de publication
Date de publication:
Apr 2022
Apr 2022
Historique:
revised:
10
07
2021
received:
25
05
2021
accepted:
15
07
2021
pubmed:
17
7
2021
medline:
25
3
2022
entrez:
16
7
2021
Statut:
ppublish
Résumé
To compare characteristics, disease course, and prognosis of spontaneous versus iatrogenic benign metastasizing leiomyoma (BML). A retrospective cohort study comparing iatrogenic and spontaneous BML. Twenty cases were included, 12 (60%) spontaneous and 8 (40.0%) iatrogenic with a median follow up of 3.4 years. The rate of asymptomatic presentation did not differ between study groups (P = 0.157). When symptoms occurred, dyspnea was more common in the spontaneous group (66.6% vs 0%, P = 0.023) and self-palpation was more common in the iatrogenic group (57.1% vs 0%, P = 0.023). Intravascular masses were more common in the spontaneous group (66.6% vs 0%, P = 0.029). Rate of BML located in abdominal/pelvic cavity was higher in the iatrogenic group (100.0% vs 41.6%, P = 0.014). Of the 12 women in the spontaneous group, 50% had recurrent disease following surgical resection or unresectable lesions surgical resection was successfully attempted in seven of the eight (87.5%) women in the iatrogenic group, with no residual/recurrent disease. None of the patients died of her disease. Spontaneous and iatrogenic BML can probably be regarded as two separate etiologies of the same pathologic phenomenon, usually with favorable prognosis. However, spontaneous BML may have a less favorable course.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
110-114Informations de copyright
© 2021 International Federation of Gynecology and Obstetrics.
Références
Awonuga AO, Shavell VI, Imudia AN, Rotas M, Diamond MP, Puscheck EE. Pathogenesis of benign metastasizing leiomyoma: a review. Obstet Gynecol Surv. 2010;65:189-195.
Chen S, Liu RM, Li T. Pulmonary benign metastasizing leiomyoma: a case report and literature review. J Thorac Dis. 2014;6(6):E92-E98.
Chen S, Zhang Y, Zhang J, et al. Pulmonary benign metastasizing leiomyoma from uterine leiomyoma. World J Surg Oncol. 2013;11:163.
Miller J, Shoni M, Siegert C, Lebenthal A, Godleski J, McNamee C. Benign metastasizing leiomyomas to the lungs: an institutional case series and a review of the recent literature. Ann Thorac Surg. 2016;101:253-258.
Anand N, Handler M, Khan A, Wagreich A, Calhoun S. Disseminated peritoneal leiomyomatosis status post laparoscopic hysterectomy with morcellation. J Radiol Case Rep. 2016;10(12):12-18.
Park BY, Leslie KO, Chen L, Vaszar LT, Cornella JL. A case of simultaneous benign metastasizing leiomyomas and disseminated peritoneal leiomyomatosis following endoscopic power morcellation for uterine disease. Female Pelvic Med Reconstr Surg. 2017;23(1):e1-e3.
Noel NL, Isaacson KB. Morcellation complications: from direct trauma to inoculation. Best Pract Res Clin Obstet Gynaecol. 2016;35:37-43.
Zhang HM, Christianson LA, Templeman CL, Lentz SE. Non-malignant sequelae after unconfined power morcellation. J Minim Invasive Gynecol. 2019;26(3):434-440.
Cucinella G, Granese R, Calagna G, Somigliana E, Perino A. Parasitic myomas after laparoscopic surgery: an emerging complication in the use of morcellator? Description of four cases. Fertil Steril. 2011;96(2):e90-e96.
Matos F, Santiago C, Silva D. Multisystemic benign metastasizing leiomyoma: an unusual condition with an atypical clinical presentation. Case Rep Radiol. 2019;2019:4.
Ofori K, Fernandes H, Cummings M, Colby T, Saqi A. Benign metastasizing leiomyoma presenting with miliary pattern and fatal outcome: Case report with molecular analysis & review of the literature. Respir Med Case Rep. 2019;27:100831.
US Food and Drug Administration. Updated laparoscopic uterine power morcellation in hysterectomy and myomectomy: FDA safety communication. 2014. https://www.burgsimpson.com/wp-content/uploads/2016/08/FDA_Safety_Communication_11-24-2014.pdf. Accessed November 24, 2014.
Kutay V, Tuncer M, Harman M, Ekim H, Yakut C. Intracardiac extension of intravenous leiomyoma. Tex Heart Inst J. 2005;32(2):232-234.
Norris HJ, Parmley T. Mesenchymal tumors of the uterus. V. Intravenous leiomyomatosis. A clinical and pathologic study of 14 cases. Cancer. 1975;36(6):2164-2178.
Kim Y-N, Eoh KJ, Lee J-Y, et al. Aberrant uterine leiomyomas with extrauterine manifestation: intravenous leiomyomatosis and benign metastasizing leiomyomas. Obstet Gynecol Sci. 2018;61(4):509-519.
Lee HJ, Choi J, Kim KR. Pulmonary benign metastasizing leiomyoma associated with intravenous leiomyomatosis of the uterus: clinical behavior and genomic changes supporting a transportation theory. Int J Gynecol Pathol. 2008;27(3):340-345.
Joo HJ, Han SS, Kwon JT, Park ES, Jung YY, Kim HK. Epidural intracranial metastasis from benign leiomyoma: a case report with literature review. Clin Neurol Neurosurg. 2013;115(7):1180-1183.
Houck WV, Broderick TJ, Cohen SA, Cohen NM. Benign metastasizing leiomyoma. Surg Endosc. 2002;16(4):716.
Gaur K, Majumdar K, Kisku N, Gondal R, Sakhuja P, Satsangi DK. Primary intracardiac leiomyoma arising from cardiomyocyte progenitors at the right ventriculoseptal interface: case report with literature review. Cardiovasc Pathol. 2017;28:46-50.
Martin E. Leiomyomatous lung lesions: a proposed classification. Am J Roentgenol. 1983;141:269-272.
Meddeb M, Chow RD, Whipps R, Haque R. The heart as a site of metastasis of benign metastasizing leiomyoma: case report and review of the literature. Case Rep Cardiol. 2018;2018:5.
Zong D, He W, Li J, Peng H, Chen P, Ouyang R. Concurrent benign metastasizing leiomyoma in the lung and lumbar spine with elevated standardized uptake value level in positron-emission tomography computed tomography: a case report and literature review. Medicine. 2018;97(27):e11334.
Sawai Y, Shimizu T, Yamanaka Y, Niki M, Nomura S. Benign metastasizing leiomyoma and 18-FDG-PET/CT: a case report and literature review. Oncol Lett. 2017;14(3):3641-3646.
Abu Saadeh F, Riain CO, Cormack CM, Gleeson N. Lung metastases from benign uterine leiomyoma: does 18-FDG-PET/CT have a role to play? Ir J Med Sci, 2019;188(2):619-624.
Wei WT, Chen PC. Benign metastasizing leiomyoma of the lung: a case report and literature review. Oncol Lett. 2015;10(1):307-312.
Hoetzenecker K, Ankersmit HJ, Aigner C, et al. Consequences of a wait-and-see strategy for benign metastasizing leiomyomatosis of the lung. Ann Thorac Surg. 2009;87(2):613-614.
Rivera JA, Christopoulos S, Small D, Trifiro M. Hormonal manipulation of benign metastasizing leiomyomas: report of two cases and review of the literature. J Clin Endocrinol Metab. 2004;89(7):3183-3188.
Castagneto Gissey L, Mariano G, Musleh L, et al. Massive pelvic recurrence of uterine leiomyomatosis with intracaval-intracardiac extension: video case report and literature review. BMC Surg. 2017;17(1):118.