Pediatric auto-immune encephalitis.


Journal

Current problems in pediatric and adolescent health care
ISSN: 1538-3199
Titre abrégé: Curr Probl Pediatr Adolesc Health Care
Pays: United States
ID NLM: 101134613

Informations de publication

Date de publication:
07 2021
Historique:
pubmed: 18 7 2021
medline: 9 11 2021
entrez: 17 7 2021
Statut: ppublish

Résumé

Pediatric Auto-Immune Encephalitis (PAE) is a neuro-inflammatory disorder with a varied presentation. The discovery of the Anti NMDA receptor and other antibodies as the causative agents of PAE, has led to an increased need for guidelines for diagnosis and management of these disorders. PAE remains a challenging group of disorders due to their varying presentations and etiology with a prolonged clinical course. The wide spectrum of clinical symptoms involves altered mental status, movement disorders, acute behavioral changes, psychosis, delirium, seizures, and insomnia. This group of disorders was recently recognized in the children. This review provides clinicians with information on the most common PAE disorders, the spectrum of their clinical presentation, diagnostic tests and treatment protocols based on the current literature.

Identifiants

pubmed: 34272178
pii: S1538-5442(21)00086-9
doi: 10.1016/j.cppeds.2021.101031
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

101031

Informations de copyright

Copyright © 2021 Elsevier Inc. All rights reserved.

Auteurs

Ajay Goenka (A)

Dayton Children Hospital, Wright State University Boonshoft School of Medicine, 1 Children Plaza, Dayton Ohio 45404. Electronic address: goenkaa@childrensdayton.org.

Mahesh Chikkannaiah (M)

Dayton Children Hospital, Wright State University Boonshoft School of Medicine, 1 Children Plaza, Dayton Ohio 45404. Electronic address: Chikkannaiahm@childrensdayton.org.

Gogi Kumar (G)

Dayton Children Hospital, Wright State University Boonshoft School of Medicine, 1 Children Plaza, Dayton Ohio 45404. Electronic address: kumarg@childrensdayton.org.

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Classifications MeSH