Aircraft noise exposure drives the activation of white blood cells and induces microvascular dysfunction in mice.
Aircraft noise exposure
Dorsal skinfold model
Inflammatory phenotype
Microvascular dysfunction
Phagocytic NADPH oxidase
Plasma proteome
Journal
Redox biology
ISSN: 2213-2317
Titre abrégé: Redox Biol
Pays: Netherlands
ID NLM: 101605639
Informations de publication
Date de publication:
10 2021
10 2021
Historique:
received:
25
05
2021
revised:
03
07
2021
accepted:
05
07
2021
pubmed:
19
7
2021
medline:
26
10
2021
entrez:
18
7
2021
Statut:
ppublish
Résumé
Epidemiological studies showed that traffic noise has a dose-dependent association with increased cardiovascular morbidity and mortality. Whether microvascular dysfunction contributes significantly to the cardiovascular health effects by noise exposure remains to be established. The connection of inflammation and immune cell interaction with microvascular damage and functional impairment is also not well characterized. Male C57BL/6J mice or gp91phox
Identifiants
pubmed: 34274810
pii: S2213-2317(21)00222-6
doi: 10.1016/j.redox.2021.102063
pmc: PMC8313840
pii:
doi:
Substances chimiques
NADPH Oxidases
EC 1.6.3.-
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
102063Subventions
Organisme : Cancer Research UK
ID : C157/A255140
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 208402/Z/17/Z
Pays : United Kingdom
Informations de copyright
Copyright © 2021 The Author(s). Published by Elsevier B.V. All rights reserved.