Late-Onset Peripheral T-Cell Lymphoma Not Otherwise Specified in a Liver Transplant Recipient: A Rare Subtype of Posttransplant Lymphoproliferative Disorder.
CHOEP, Cyclophosphamide, Doxorubicin, Etoposide, Vincristine, Prednisolone
EBV, Epstein-Barr Virus
Epstein-Barr virus
NK, Natural Killer Cells
PET, Positron Emission Tomography
PTLD NOS, Posttransplant Lymphoproliferative Disorder Not Otherwise Specified
PTLD, Posttransplant Lymphoproliferative Disorder
chemotherapy
liver transplantation
peripheral T-cell lymphoma not otherwise specified
remission
Journal
Journal of clinical and experimental hepatology
ISSN: 0973-6883
Titre abrégé: J Clin Exp Hepatol
Pays: India
ID NLM: 101574137
Informations de publication
Date de publication:
Historique:
received:
29
06
2020
accepted:
22
09
2020
entrez:
19
7
2021
pubmed:
20
7
2021
medline:
20
7
2021
Statut:
ppublish
Résumé
Posttransplant lymphoproliferative disorder (PTLD) is a rare complication seen in the period after liver transplant. The commonest subtype is B-cell PTLD which is usually associated with Epstein-Barr virus (EBV) infection. T-cell PTLD is rare and the association with EBV is again rarer. Our patient, a 21-year-old young adult, presented to us with generalized lymphadenopathy, 5 years after liver transplantation. The biopsy of the lymph node was suggestive of peripheral T-cell lymphoma not otherwise specified, which was associated with EBV infection. The Positron emission tomography and computerised tomography (PET-CT) scan showed stage 3 disease. He was treated with standard cyclophosphamide, doxorubicin, etoposide, vincristine, and prednisolone chemotherapy and is currently in remission. Peripheral T-cell lymphoma not otherwise specified is a rare subtype of PTLD and its association with EBV is even more rare. A few patients can achieve complete remission with standard chemotherapy.
Identifiants
pubmed: 34276157
doi: 10.1016/j.jceh.2020.09.002
pii: S0973-6883(20)30141-9
pmc: PMC8267348
doi:
Types de publication
Case Reports
Langues
eng
Pagination
511-514Informations de copyright
© 2020 Indian National Association for Study of the Liver. Published by Elsevier B.V. All rights reserved.
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