Volatile Versus Intravenous Anesthetics in Cardiac Anesthesia: a Narrative Review.

Cardiac surgery Desflurane Propofol Sevoflurane Total intravenous anesthesia Volatile anesthetics

Journal

Current anesthesiology reports
ISSN: 1523-3855
Titre abrégé: Curr Anesthesiol Rep
Pays: United States
ID NLM: 100888957

Informations de publication

Date de publication:
2021
Historique:
accepted: 18 06 2021
pubmed: 20 7 2021
medline: 20 7 2021
entrez: 19 7 2021
Statut: ppublish

Résumé

The present review addresses clinicians and gives an overview about the experimental rationale for pharmacological conditioning associated with volatile anesthetics, opioids, and propofol; the current clinical data; and the technical considerations regarding the clinical routine in cardiac anesthesia. Volatile anesthetics have been standard of care for general anesthesia for cardiac surgery, especially while using cardiopulmonary bypass. The 2019 published MYRIAD trial was not able to show a difference in mortality or cardiac biomarkers for volatile anesthetics compared to total intravenous anesthesia (TIVA), raising the question of equivalence with respect to patient outcome. Reviewing the literature, the scientific foundation for the belief of clinically relevant conditioning by uninterrupted administration of a volatile anesthetic is weak. TIVA can also be performed safely in patients undergoing cardiac surgery.

Identifiants

pubmed: 34276252
doi: 10.1007/s40140-021-00466-1
pii: 466
pmc: PMC8271298
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

275-283

Informations de copyright

© The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2021.

Déclaration de conflit d'intérêts

Conflict of InterestThe authors do not have any potential conflicts of interest to disclose.

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Auteurs

Christopher Uhlig (C)

Department of Cardiac Anesthesiology, Heart Center Dresden University Hospital, Fetscherstr. 76, 01307 Dresden, Germany.

Jakob Labus (J)

Department of Anesthesiology and Intensive Care Medicine, University Hospital and Medical Faculty, Cologne University, Albertus-Magnus-Platz, 50923 Cologne, Germany.

Classifications MeSH