The effects of aging on molecular modulators of human embryo implantation.

Embryology Omics

Journal

iScience
ISSN: 2589-0042
Titre abrégé: iScience
Pays: United States
ID NLM: 101724038

Informations de publication

Date de publication:
23 Jul 2021
Historique:
received: 08 10 2020
revised: 26 02 2021
accepted: 16 06 2021
entrez: 19 7 2021
pubmed: 20 7 2021
medline: 20 7 2021
Statut: epublish

Résumé

Advancing age has a negative impact on female fertility. As implantation rates decline during the normal maternal life course, age-related, embryonic factors are altered and our inability to monitor these factors in an unbiased genome-wide manner

Identifiants

pubmed: 34278260
doi: 10.1016/j.isci.2021.102751
pii: S2589-0042(21)00719-7
pmc: PMC8271113
doi:

Types de publication

Journal Article

Langues

eng

Pagination

102751

Subventions

Organisme : Medical Research Council
ID : MR/K020501/1
Pays : United Kingdom

Informations de copyright

© 2021 The Authors.

Déclaration de conflit d'intérêts

Author P.N. has a pending patent application (application number: GB 2107813.4). This does not alter the authors’ adherence to the journal’s policies on sharing data and materials. All remaining authors declare no conflicting interests.

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Auteurs

Panagiotis Ntostis (P)

Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, LS2 9JT, UK.
Genetics Department, Medical school, National and Kapodistrian University of Athens, Athens, 115 27, Greece.

Grace Swanson (G)

Department of Obstetrics and Gynecology and the Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, MI 48201, USA.

Georgia Kokkali (G)

Genesis Athens Clinic, Reproductive Medicine Unit, Athens, 152 32, Greece.

David Iles (D)

Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, LS2 9JT, UK.

John Huntriss (J)

Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, LS2 9JT, UK.

Agni Pantou (A)

Genesis Athens Clinic, Reproductive Medicine Unit, Athens, 152 32, Greece.

Maria Tzetis (M)

Genetics Department, Medical school, National and Kapodistrian University of Athens, Athens, 115 27, Greece.

Konstantinos Pantos (K)

Genesis Athens Clinic, Reproductive Medicine Unit, Athens, 152 32, Greece.

Helen M Picton (HM)

Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, LS2 9JT, UK.

Stephen A Krawetz (SA)

Department of Obstetrics and Gynecology and the Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, MI 48201, USA.

David Miller (D)

Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, LS2 9JT, UK.

Classifications MeSH