Biodegradable and Dual-Responsive Polypeptide-Shelled Cyclodextrin-Containers for Intracellular Delivery of Membrane-Impermeable Cargo.
biodegradable
cyclodextrin
dual-responsive
intracellular delivery
polypeptides
Journal
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
ISSN: 2198-3844
Titre abrégé: Adv Sci (Weinh)
Pays: Germany
ID NLM: 101664569
Informations de publication
Date de publication:
09 2021
09 2021
Historique:
revised:
01
07
2021
received:
19
02
2021
pubmed:
20
7
2021
medline:
11
2
2022
entrez:
19
7
2021
Statut:
ppublish
Résumé
The transport of membrane impermeable compounds into cells is a prerequisite for the efficient cellular delivery of hydrophilic and amphiphilic compounds and drugs. Transport into the cell's cytosolic compartment should ideally be controllable and it should involve biologically compatible and degradable vehicles. Addressing these challenges, nanocontainers based on cyclodextrin amphiphiles that are stabilized by a biodegradable peptide shell are developed and their potential to deliver fluorescently labeled cargo into human cells is analyzed. Host-guest mediated self-assembly of a thiol-containing short peptide or a cystamine-cross-linked polypeptide shell on cyclodextrin vesicles produce short peptide-shelled (SPSV
Identifiants
pubmed: 34278745
doi: 10.1002/advs.202100694
pmc: PMC8456233
doi:
Substances chimiques
Cyclodextrins
0
Peptides
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e2100694Subventions
Organisme : Deutsche Forschungsgemeinschaft
ID : SFB 858/B19
Organisme : Deutsche Forschungsgemeinschaft
ID : GE514/6-3
Informations de copyright
© 2021 The Authors. Advanced Science published by Wiley-VCH GmbH.
Références
Chemistry. 2010 Jul 26;16(28):8300-6
pubmed: 20593445
Macromol Rapid Commun. 2020 Sep;41(18):e2000049
pubmed: 32419159
ACS Appl Bio Mater. 2020 Apr 20;3(4):2048-2057
pubmed: 35025326
Adv Drug Deliv Rev. 1999 Nov 10;40(1-2):3-18
pubmed: 10837777
J Cell Sci. 2011 Nov 1;124(Pt 21):3695-705
pubmed: 22045733
Nucleic Acids Res. 1996 Aug 1;24(15):2924-9
pubmed: 8760875
Curr Opin Microbiol. 2010 Feb;13(1):106-12
pubmed: 20079678
Adv Sci (Weinh). 2019 Oct 24;6(24):1901935
pubmed: 31871866
J Am Chem Soc. 2013 Nov 27;135(47):17655-8
pubmed: 24000948
J Control Release. 2021 Jun 10;334:290-302
pubmed: 33905803
Angew Chem Int Ed Engl. 2020 Aug 3;59(32):13526-13530
pubmed: 32383236
Arch Biochem Biophys. 1958 Apr;74(2):443-50
pubmed: 13534673
Proc Natl Acad Sci U S A. 2000 Jan 18;97(2):745-50
pubmed: 10639150
Front Pharmacol. 2015 Dec 01;6:286
pubmed: 26648870
Angew Chem Int Ed Engl. 2000 Dec 1;39(23):4324-4326
pubmed: 29711925
J Am Chem Soc. 2015 Feb 11;137(5):1967-71
pubmed: 25599114
Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2021 Mar;13(2):e1678
pubmed: 33155421
Proc Natl Acad Sci U S A. 2006 Sep 12;103(37):13872-7
pubmed: 16950881
Angew Chem Int Ed Engl. 2020 Feb 17;59(8):2962-2972
pubmed: 31364243
Nat Med. 2004 Mar;10(3):310-5
pubmed: 14770178
Adv Drug Deliv Rev. 2004 Apr 23;56(7):999-1021
pubmed: 15066757
Antioxid Redox Signal. 2011 Aug 1;15(3):657-68
pubmed: 21506690
Chem Soc Rev. 2012 Apr 7;41(7):2867-84
pubmed: 22282265
Angew Chem Int Ed Engl. 2019 Sep 9;58(37):12840-12860
pubmed: 30633433
ACS Appl Bio Mater. 2021 Apr 19;4(4):3264-3275
pubmed: 35014413
Ther Deliv. 2016;7(5):319-34
pubmed: 27075952
Mol Pharm. 2010 Aug 2;7(4):1260-5
pubmed: 20476763
Adv Sci (Weinh). 2021 Sep;8(18):e2100694
pubmed: 34278745
Nat Cell Biol. 2006 Aug;8(8):843-8
pubmed: 16829952
J Immunol. 2005 Feb 15;174(4):1791-800
pubmed: 15699105
Biochem Biophys Res Commun. 2007 Feb 2;353(1):26-32
pubmed: 17184736
Nat Rev Drug Discov. 2014 Nov;13(11):813-27
pubmed: 25287120
Proc Natl Acad Sci U S A. 2010 Nov 23;107(47):20246-50
pubmed: 21048084
Anal Bioanal Chem. 2002 Jul;373(4-5):266-76
pubmed: 12110978
World J Gastroenterol. 2018 Sep 14;24(34):3834-3848
pubmed: 30228778
PLoS Pathog. 2020 Nov 2;16(11):e1009013
pubmed: 33137165
Nat Rev Microbiol. 2009 May;7(5):333-40
pubmed: 19369949
ACS Nano. 2011 Jun 28;5(6):4434-47
pubmed: 21563770
Biomaterials. 2010 Feb;31(5):923-33
pubmed: 19853293
J Control Release. 2010 Aug 3;145(3):182-95
pubmed: 20226220
ACS Nano. 2011 Mar 22;5(3):1657-69
pubmed: 21344890
Angew Chem Int Ed Engl. 2017 Aug 1;56(32):9603-9607
pubmed: 28485535
Mol Aspects Med. 2009 Feb-Apr;30(1-2):1-12
pubmed: 18796312
Mol Cell. 2008 Jun 6;30(5):547-56
pubmed: 18538653
Adv Sci (Weinh). 2019 Feb 04;6(7):1801987
pubmed: 31139556
Molecules. 2018 Jan 30;23(2):
pubmed: 29385755
PLoS One. 2007 Nov 07;2(11):e1144
pubmed: 17987124
J Control Release. 2021 Apr 10;332:269-284
pubmed: 33662455
Adv Mater. 2016 Feb 10;28(6):1109-28
pubmed: 26509964
J Control Release. 2008 Dec 18;132(3):230-5
pubmed: 18627784
Adv Drug Deliv Rev. 2013 Jan;65(1):36-48
pubmed: 23036225
Biomacromolecules. 2018 Aug 13;19(8):3572-3585
pubmed: 29906389