Feasibility, acceptability, and efficacy of an adopted novel self-management intervention among people with epilepsy in Uganda.
Comorbidity
Depression
Epilepsy
Quality of life
Seizures
Stigma
Journal
Epilepsy & behavior : E&B
ISSN: 1525-5069
Titre abrégé: Epilepsy Behav
Pays: United States
ID NLM: 100892858
Informations de publication
Date de publication:
09 2021
09 2021
Historique:
received:
31
03
2021
revised:
31
05
2021
accepted:
28
06
2021
pubmed:
20
7
2021
medline:
15
9
2021
entrez:
19
7
2021
Statut:
ppublish
Résumé
Epilepsy is a common neurological condition characterized by poor quality of life and associated stigma. Studies in long-term health conditions suggest that self-management interventions improve the quality of life (QoL) and reduce the perceived stigma among people with epilepsy (PWE). Yet, the utilization of these interventions remains low in sub-Saharan Africa. We investigated the feasibility, acceptability, and preliminary efficacy of an adopted novel self-management intervention, Self-management for people with epilepsy and a history of negative health events (SMART) among PWE in Uganda. A two-year, uncontrolled, prospective pilot study in Ugandans with epilepsy was conducted. Adults aged ≥ 18 years with epilepsy attending a neurology outpatient clinic were enrolled. Using a nurse led and peer educator interactions; nine self-management approach sessions (1 individual session and 8 group sessions) were conducted. The primary outcome was QoL, perceived stigma and depression in PWE at 24-month follow-up using the Quality Of Life In Epilepsy 31 (QOLIE-31) scale and perceived stigma using the Kilifi stigma score and Neurological disorders depression index for epilepsy (NDDI-E). There were 17 individuals and their caregivers who were enrolled into this study with a mean age of 23.47 (SD = 5.3) years. The study intervention was feasible and acceptable within our settings. Overall, quality of life, stigma level, depression, and seizure frequency in the past 30 days were significantly improved from the baseline scores before the intervention with p-values of <0.0001, <0.0001, 0.004, and <0.0001, respectively. The SMART intervention engages individuals to actively participate in self-management, and can help reduce depressive symptom severity in PWE. Given the high morbidity and mortality associated with epilepsy, additional research is needed to better identify how SMART might be implemented in routine care settings.
Sections du résumé
BACKGROUND
Epilepsy is a common neurological condition characterized by poor quality of life and associated stigma. Studies in long-term health conditions suggest that self-management interventions improve the quality of life (QoL) and reduce the perceived stigma among people with epilepsy (PWE). Yet, the utilization of these interventions remains low in sub-Saharan Africa.
OBJECTIVES
We investigated the feasibility, acceptability, and preliminary efficacy of an adopted novel self-management intervention, Self-management for people with epilepsy and a history of negative health events (SMART) among PWE in Uganda.
DESIGN
A two-year, uncontrolled, prospective pilot study in Ugandans with epilepsy was conducted.
PARTICIPANTS
Adults aged ≥ 18 years with epilepsy attending a neurology outpatient clinic were enrolled.
INTERVENTION
Using a nurse led and peer educator interactions; nine self-management approach sessions (1 individual session and 8 group sessions) were conducted.
MAIN OUTCOME MEASURES
The primary outcome was QoL, perceived stigma and depression in PWE at 24-month follow-up using the Quality Of Life In Epilepsy 31 (QOLIE-31) scale and perceived stigma using the Kilifi stigma score and Neurological disorders depression index for epilepsy (NDDI-E).
RESULTS
There were 17 individuals and their caregivers who were enrolled into this study with a mean age of 23.47 (SD = 5.3) years. The study intervention was feasible and acceptable within our settings. Overall, quality of life, stigma level, depression, and seizure frequency in the past 30 days were significantly improved from the baseline scores before the intervention with p-values of <0.0001, <0.0001, 0.004, and <0.0001, respectively.
SIGNIFICANCE
The SMART intervention engages individuals to actively participate in self-management, and can help reduce depressive symptom severity in PWE. Given the high morbidity and mortality associated with epilepsy, additional research is needed to better identify how SMART might be implemented in routine care settings.
Identifiants
pubmed: 34280726
pii: S1525-5050(21)00461-3
doi: 10.1016/j.yebeh.2021.108200
pmc: PMC10164612
mid: NIHMS1721470
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
108200Subventions
Organisme : FIC NIH HHS
ID : K43 TW010401
Pays : United States
Informations de copyright
Copyright © 2021 Elsevier Inc. All rights reserved.
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