Among respiratory symptoms, wheeze associates most strongly with impaired lung function in adults with asthma: a long-term prospective cohort study.
asthma epidemiology
clinical epidemiology
Journal
BMJ open respiratory research
ISSN: 2052-4439
Titre abrégé: BMJ Open Respir Res
Pays: England
ID NLM: 101638061
Informations de publication
Date de publication:
07 2021
07 2021
Historique:
received:
17
05
2021
accepted:
19
06
2021
entrez:
20
7
2021
pubmed:
21
7
2021
medline:
25
11
2021
Statut:
ppublish
Résumé
Asthma is a common disease and a major public health concern. Respiratory symptoms are related to its prognosis, which in turn associates with lung function. Still this association on a long-term basis is not entirely understood. To study the association of the type and number of respiratory symptoms with FEV A population-based cohort of adults with asthma was examined at study entry between 1986 and 2001 and at follow-up between 2012 and 2014, and n=977 had valid measurements of FEV For both sexes recurrent wheeze and dyspnoea were associated with lower FEV Particularly recurrent wheeze and a higher number of respiratory symptoms may predict lower lung function also in the long run among women and men with asthma.
Sections du résumé
BACKGROUND
Asthma is a common disease and a major public health concern. Respiratory symptoms are related to its prognosis, which in turn associates with lung function. Still this association on a long-term basis is not entirely understood.
AIM
To study the association of the type and number of respiratory symptoms with FEV
METHOD
A population-based cohort of adults with asthma was examined at study entry between 1986 and 2001 and at follow-up between 2012 and 2014, and n=977 had valid measurements of FEV
RESULTS
For both sexes recurrent wheeze and dyspnoea were associated with lower FEV
CONCLUSIONS
Particularly recurrent wheeze and a higher number of respiratory symptoms may predict lower lung function also in the long run among women and men with asthma.
Identifiants
pubmed: 34281917
pii: 8/1/e000981
doi: 10.1136/bmjresp-2021-000981
pmc: PMC8291305
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: All authors have completed the ICMJE COI disclosure form.NBB has nothing to disclose. AL reports personal fees from Boehringer-Ingelheim, AstraZeneca, Novartis and GlaxoSmithKline outside the submitted work. CS reports personal fees from AstraZeneca, Boehringer-Ingelheim and Novartis outside the submitted work.MA has nothing to disclose. LH has nothing to disclose. SAV reports personal fees from AstraZeneca and Boehringer-Ingelheim outside the submitted work. HK reports personal fees and non-financial support from AstraZeneca, Boehringer-Ingelheim and Orion Pharma; personal fees from Chiesi Pharma AB, Novartis, Mundipharma, SanofiGenzyme and GlaxoSmithKline; outside of the submitted work.BL reports personal fees from Novartis and Sanofi; grants from AstraZeneca; outside the submitted work. ER has nothing to disclose. HB reports personal fees from AstraZeneca and Boehringer Ingelheim outside the submitted work.
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