Current and Emerging Strategies for Prediction and Diagnosis of Prelabour Rupture of the Membranes: A Narrative Review.
Fern test
IL-8
PROM
alpha-fetoprotein
amniotic fluid interleukin-8
biochemical markers
biomarkers
chorioamnionitis
foetal fibronectin
insulin-like growth factor binding protein-1
monoclonal/polyclonal antibody immunoassay tests
placental alpha microglobulin-1
placental protein 14
prelabour rupture of membranes
preterm prelabour rupture of membranes
Journal
The Malaysian journal of medical sciences : MJMS
ISSN: 1394-195X
Titre abrégé: Malays J Med Sci
Pays: Malaysia
ID NLM: 101126308
Informations de publication
Date de publication:
Jun 2021
Jun 2021
Historique:
received:
01
09
2020
accepted:
25
10
2020
entrez:
21
7
2021
pubmed:
22
7
2021
medline:
22
7
2021
Statut:
ppublish
Résumé
Prelabour rupture of membranes (PROM) refers to the disruption of foetal membranes before the onset of labour, resulting in the leakage of amniotic fluid. PROM complicates 3% and 8% of preterm and term pregnancies, respectively. Accurate and timely diagnosis is crucial for effective management to prevent adverse maternal- and foetal-outcomes. The diagnosis of equivocal PROM cases with traditional methods often becomes challenging in current obstetrics practice; therefore, various novel biochemical markers have emerged as promising diagnostic tools. This narrative review is sought to review the published data to understand the current and emerging trends in diagnostic modalities in term and preterm pregnancies complicated with PROM and the potential role of various markers for predicting preterm PROM (pPROM) and chorioamnionitis in women with pPROM.
Identifiants
pubmed: 34285641
doi: 10.21315/mjms2021.28.3.2
pii: 02mjms2803_ra
pmc: PMC8260062
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
5-17Informations de copyright
© Penerbit Universiti Sains Malaysia, 2021.
Déclaration de conflit d'intérêts
Conflict of Interest None.
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