A primary mediastinal germ cell tumor of yolk sac type: case report.
Antineoplastic Combined Chemotherapy Protocols
/ administration & dosage
Biopsy
Chest Pain
/ etiology
Combined Modality Therapy
Endodermal Sinus Tumor
/ diagnosis
Etoposide
/ administration & dosage
Humans
Ifosfamide
/ administration & dosage
Mediastinal Neoplasms
/ diagnosis
Platinum Compounds
/ administration & dosage
Tomography, X-Ray Computed
Young Adult
Germ cell tumors
case report
mediastinum
yolk sac tumor
Journal
The Pan African medical journal
ISSN: 1937-8688
Titre abrégé: Pan Afr Med J
Pays: Uganda
ID NLM: 101517926
Informations de publication
Date de publication:
2021
2021
Historique:
received:
25
05
2020
accepted:
16
03
2021
entrez:
21
7
2021
pubmed:
22
7
2021
medline:
5
8
2021
Statut:
epublish
Résumé
The mediastinal malignant germ cells tumor represents less than 0.5% of thoracic tumors, although the mediastinum is one of the main extragonadic locations of these tumors. In the majority of cases, young people are those most affected. The prognosis of mediastinal malignant germ cells tumors is poor, especially non-seminomatous germ tumors. In this article, we report a rare case of a young 19-years-old patient treated for a mediastinal germ cell tumor of yolk sac. The patient presented a chest pain; the chest computed tomography (CT) showed a right paramedian mediastinal mass with a pleural effusion associated with supraclavicular and cervical lymph nodes. Biopsy revealed a non-seminomatousgerm cell tumor of yolk sac. The exams showed elevated alpha-fetoprotein (AFP), without any meaningful elevation of other serictumor markers. The patient received 4 cycles of chemotherapy based on etoposide, ifosfamide and platinum salts then a complete excision of the mass.
Identifiants
pubmed: 34285753
doi: 10.11604/pamj.2021.38.330.23730
pii: PAMJ-38-330
pmc: PMC8265249
doi:
Substances chimiques
Platinum Compounds
0
Etoposide
6PLQ3CP4P3
Ifosfamide
UM20QQM95Y
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
330Informations de copyright
Copyright: Khadija Darif et al.
Déclaration de conflit d'intérêts
The authors declare no competing interests.
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