Methodologies to Increase the Level of Evidence of Real-life Proton Therapy in Head and Neck Tumors.
head and neck cancer
model-based approach
proton therapy
randomized trials
registries
Journal
International journal of particle therapy
ISSN: 2331-5180
Titre abrégé: Int J Part Ther
Pays: United States
ID NLM: 101674108
Informations de publication
Date de publication:
2021
2021
Historique:
received:
31
08
2020
accepted:
12
02
2021
entrez:
21
7
2021
pubmed:
22
7
2021
medline:
22
7
2021
Statut:
epublish
Résumé
This review aims to present and assess available and new methodologies to increase the clinical evidence of proton therapy data for patients with head and neck cancer. Despite the increasing number of scientific reports showing the feasibility and effectiveness of proton therapy in head and neck cancer, clinical evidence on the potential benefits of its use remains low for several reasons. In this article, the pros and cons of consolidated and new methodologies in this setting such as randomized clinical trials, the model-based approach, and the use of prospective multicentric registries will be detailed.
Identifiants
pubmed: 34285959
doi: 10.14338/IJPT-20-00051.1
pii: THEIJPT-D-20-00051R1
pmc: PMC8270108
doi:
Types de publication
Journal Article
Langues
eng
Pagination
328-338Informations de copyright
©Copyright 2021 The Author(s).
Déclaration de conflit d'intérêts
Conflicts of Interest: The authors have no conflicts of interest to disclose.
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