[Mycoplasma genitalium in Primary Care: Prevalence and azithromycin resistance in Santiago de Compostela Health Care Area].

Mycoplasma genitalium en Atención Primaria: Prevalencia y resistencia a azitromicina en el Área Sanitaria de Santiago de Compostela.

Journal

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia
ISSN: 1988-9518
Titre abrégé: Rev Esp Quimioter
Pays: Spain
ID NLM: 9108821

Informations de publication

Date de publication:
Oct 2021
Historique:
pubmed: 22 7 2021
medline: 25 11 2021
entrez: 21 7 2021
Statut: ppublish

Résumé

Mycoplasma genitalium is associated with persistent/recurrent sexually transmitted infections. The aim of this work was to estimate the prevalence and azithromycin resistance of M. genitalium in general population that was attended at Primary Care of Santiago de Compostela Health Care Area. The study was carried out in 2019 in general population of Santiago de Compostela Health Care Area. Real-time multiplex PCR was used for screening of sexually transmitted infections associated pathogens and detection of mutations in the 23S rRNA gene. A total of 502 women and 532 men were studied. The prevalence of M. genitalium was 2,4% in men and 2,9% in women. Overall azithromycin resistance was 20% all of them detected in men. The mutations found were A2059G, A2058G and A2058T. Although the proportion of M. genitalium infection is low, the high percentage of azithromycin resistance detected supports the relevance of these data in order to the right management of the patients with sexually transmitted diseases and, so as, to avoid the emergence of resistance in other pathogens of the urogenital tract.

Identifiants

pubmed: 34286949
doi: 10.37201/req/052.2021
pmc: PMC8638832
pii:
doi:

Substances chimiques

Anti-Bacterial Agents 0
Macrolides 0
Azithromycin 83905-01-5

Types de publication

Journal Article

Langues

spa

Sous-ensembles de citation

IM

Pagination

496-499

Informations de copyright

©The Author 2021. Published by Sociedad Española de Quimioterapia. This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)(https://creativecommons.org/licenses/by-nc/4.0/).

Références

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pubmed: 18990060
Sex Transm Dis. 2017 Aug;44(8):457-462
pubmed: 28703723
PLoS One. 2018 Aug 28;13(8):e0202428
pubmed: 30153259
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pubmed: 31451540
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pubmed: 30190106
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pubmed: 28158595
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pubmed: 31628262
Enferm Infecc Microbiol Clin (Engl Ed). 2018 Mar;36(3):169-171
pubmed: 28291669
Sex Transm Dis. 2019 Jun;46(6):395-399
pubmed: 31095102
Enferm Infecc Microbiol Clin (Engl Ed). 2019 Feb;37(2):144-145
pubmed: 29853280

Auteurs

M Rodríguez-Velasco (M)

María Rodríguez Velasco, Servicio de Microbiología, Complejo Hospitalario Universitario de Santiago de Compostela, Rúa da Choupana, s/n, 15706, Santiago de Compostela, Spain. rodvelascomaria@gmail.com.

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Classifications MeSH