In vivo preliminary test of a new biparietal bidirectional bipolar radiofrequency magnetic coupling system.
atrial Fibrillation
bipolar radiofrequency
radiofrequency ablation
Journal
Pacing and clinical electrophysiology : PACE
ISSN: 1540-8159
Titre abrégé: Pacing Clin Electrophysiol
Pays: United States
ID NLM: 7803944
Informations de publication
Date de publication:
Sep 2021
Sep 2021
Historique:
revised:
22
05
2021
received:
13
01
2021
accepted:
27
06
2021
pubmed:
22
7
2021
medline:
1
2
2022
entrez:
21
7
2021
Statut:
ppublish
Résumé
To test in vivo a new design prototype for radio frequency (RF) ablation. A prototype based on a concept of endo-epicardial biparietal bipolar RF ablation with the atrial tissue interposed and consisting of two specular endocardial-epicardial catheters was tested in four pigs (80±5 kg). The endocardial catheter was introduced into the left atrium through the left atrial appendage on the beating heart. The epicardial counterpart was placed manually on the atrial epicardial surface. The coupling of the two catheters was achieved using a neodymium magnet around the gold plate electrode, and RF was applied to the interposed tissue. The hearts were excised, and the lesions were examined using morphometric evaluation. The RF application resulted in transmural lesions in all of the four animals tested. In these animals the maximum endocardial width (W The idea of an endocardial-epicardial bidirectional biparietal bipolar radiofrequency tool such that the atrial tissue is fully interposed between the two RF poles might be promising for future clinical applications. Further research is warranted.
Sections du résumé
BACKGROUND
BACKGROUND
To test in vivo a new design prototype for radio frequency (RF) ablation.
METHODS
METHODS
A prototype based on a concept of endo-epicardial biparietal bipolar RF ablation with the atrial tissue interposed and consisting of two specular endocardial-epicardial catheters was tested in four pigs (80±5 kg). The endocardial catheter was introduced into the left atrium through the left atrial appendage on the beating heart. The epicardial counterpart was placed manually on the atrial epicardial surface. The coupling of the two catheters was achieved using a neodymium magnet around the gold plate electrode, and RF was applied to the interposed tissue. The hearts were excised, and the lesions were examined using morphometric evaluation.
RESULTS
RESULTS
The RF application resulted in transmural lesions in all of the four animals tested. In these animals the maximum endocardial width (W
CONCLUSIONS
CONCLUSIONS
The idea of an endocardial-epicardial bidirectional biparietal bipolar radiofrequency tool such that the atrial tissue is fully interposed between the two RF poles might be promising for future clinical applications. Further research is warranted.
Identifiants
pubmed: 34287967
doi: 10.1111/pace.14320
pmc: PMC9291168
doi:
Substances chimiques
Neodymium
2I87U3734A
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1585-1592Informations de copyright
© 2021 The Authors. Pacing and Clinical Electrophysiology published by Wiley Periodicals LLC.
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