A clinical pilot study of salivary gland secretion for xerostomia patients with Sjögren's syndrome using SPECT/CT.
Sjögren's syndrome
radionuclide imaging
salivary gland excretion
single photon emission computed tomography
xerostomia
Journal
Gerodontology
ISSN: 1741-2358
Titre abrégé: Gerodontology
Pays: England
ID NLM: 8215850
Informations de publication
Date de publication:
Sep 2022
Sep 2022
Historique:
received:
28
09
2020
accepted:
24
06
2021
pubmed:
22
7
2021
medline:
20
9
2022
entrez:
21
7
2021
Statut:
ppublish
Résumé
This study examined whether time-activity curves (TAC) can be used to differentiate between patients with and without Sjögren's syndrome using SPECT/CT. Thirteen xerostomia patients (5 with Sjögren's syndrome and 8 without Sjögren's syndrome) underwent SPECT/CT. Salivary gland secretion data were digitally observed, producing separate time-activity curves (TAC) for the submandibular glands and parotid glands using SPECT/CT. The salivary gland secretion fraction was defined as A (before stimulation test [counts/frame]) divided by B (after stimulation test [counts/frame]). The A/B ratios of patients with Sjögren's syndrome and those without Sjögren's syndrome were compared using the Mann-Whitney U test for nonparametric data. The A/B ratio of parotid glands with Sjögren's syndrome (1.3 ± 0.2) was significantly lower than for those without Sjögren's syndrome (2.7 ± 0.7). The A/B ratio of submandibular glands with Sjögren's syndrome (1.3 ± 0.4) is significantly lower than for those without Sjögren's syndrome (1.8 ± 0.6). The TAC for the submandibular glands and parotid glands using SPECT/CT may be useful for the objective and quantitative diagnosis of Sjögren's syndrome.
Types de publication
Journal Article
Langues
eng
Pagination
297-301Subventions
Organisme : JSPS KAKENHI
ID : 18K09754
Informations de copyright
© 2021 Gerodontology Association and John Wiley & Sons Ltd.
Références
Ogura I, Sasaki Y, Oda T, Sue M, Hayama K. Magnetic resonance sialography and salivary gland scintigraphy of parotid glands in Sjögren’s syndrome. Chin J Dent Res. 2018;21:63-68.
Manthorpe R, Frost-Larsen K, Isager H, Prause JU. Sjögren’s syndrome. A review with emphasis on immunological features. Allergy. 1981;36:139-153.
Vitali C, Bombardieri S, Jonsson R, et al. Classification criteria for Sjögren’s syndrome: a revised version of the European criteria proposed by the American- European Consensus Group. Ann Rheum Dis. 2002;61:554-558.
Shiboski CH, Shiboski SC, Seror R, et al. 2016 American college of rheumatology/ European league against rheumatism classification criteria for primary Sjögren’s syndrome: a consensus and data-driven methodology involving three international patient cohorts. Ann Rheum Dis. 2017;76:9-16.
Delli K, Vissink A, Spijkervet FK. Salivary gland biopsy for Sjögren’s syndrome. Oral Maxillofac Surg Clin North Am. 2014;26:23-33.
Gulati A, Scott J, Blythe JN, Southorn B, Brennan PA. Review of salivary papers published in the British journal of oral and maxillofacial surgery during 2009-2010. Br J Oral Maxillofac Surg. 2011;49:627-629.
Wu CB, Xi H, Zhou Q, Zhang LM. The diagnostic value of technetium 99m pertechnetate salivary gland scintigraphy in patients with certain salivary gland diseases. J Oral Maxillofac Surg. 2015;73:443-450.
Ogura I, Hayama K, Sue M, Oda T, Sasaki Y. Submandibular sialolithiasis with CT and scintigraphy: CT values and salivary gland excretion in the submandibular glands. Imaging Sci Dent. 2017;47:227-231.
Dugonjić S, Stefanović D, Ethurović B, Spasić-Jokić V, Ajdinović B. Evaluation of diagnostic parameters from parotid and submandibular dynamic salivary glands scintigraphy and unstimulated sialometry in Sjögren's syndrome. Hell J Nucl Med. 2014;17:116-122.
Aksoy T, Kiratli PO, Erbas B. Correlations between histopathologic and scintigraphic parameters of salivary glands in patients with Sjögren's syndrome. Clin Rheumatol. 2012;9:1365-1370.
Schall GL, Anderson LG, Wolf RO, et al. Xerostomia in Sjögren’s syndrome: evaluation by sequential salivary scintigraphy. JAMA. 1971;216:2109-2116.
Arrago JP, Rain JD, Brocheriou C, Rocher F. Scintigraphy of the salivary glands in Sjögren’s syndrome. J Clin Pathol. 1987;40:1463-1467.
Daniels TE, Powell MR, Sylvester RA, Talal N. An evaluation of salivary scintigraphy in Sjögren’s syndrome. Arthritis Rheum. 1979;22:809-814.
Sugihara T, Yoshimura Y. Scintigraphic evaluation of the salivary glands in patients with Sjögren’s syndrome. Int J Oral Maxillofac Surg. 1988;17:71-75.
Bohuslavizki KH, Brenner W, Wolf H, et al. Value of quantitative salivary gland scintigraphy in the early stage of Sjögren’s syndrome. Nucl Med Commun. 1995;16:917-922.
Aung W, Yamada I, Umehara I, Ohbayashi N, Yoshino N, Shibuya H. Sjögren’s syndrome: comparison of assessments with quantitative salivary gland scintigraphy and contrast sialography. J Nucl Med. 2000;41:257-262.
Suh MS, Lee WW, Kim YK, Yun PY, Kim SE. Maximum standardized uptake value of 99mTc hydroxymethylene diphosphonate SPECT/CT for the evaluation of temporomandibular joint disorder. Radiology. 2016;280:890-896.
Ogura I, Kobayashi E, Nakahara K, Igarashi K, Haga-Tsujimura M, Toshima H. Quantitative SPECT/CT imaging for medication-related osteonecrosis of the jaw: a preliminary study using volume-based parameters, comparison with chronic osteomyelitis. Ann Nucl Med. 2019;33:776-782.
Ogura I, Sasaki Y, Sue M, Oda T, Kameta A, Hayama K. Tc-99m hydroxymethylene diphosphonate SPECT/CT for the evaluation of osteonecrosis of the jaw: preliminary study on diagnostic ability of maximum standardized uptake value. Clin Radiol. 2020;75:46-50.
Toshima H, Ogura I. Assessment of inflammatory jaw pathologies using bone SPECT/CT maximum standardized uptake value. Dentomaxillofac Radiol. 2020;49:20200043.
Oohashi M, Toshima H, Hayama K, Ogura I. Gallium-67 SPECT-CT for the evaluation of head and neck: preliminary study on maximum standardized uptake value in lesions, and in the parotid and submandibular glands. Pol J Radiol. 2020;85:e224-e229.
Minami Y, Ogura I. Bone single-photon emission computed tomography-CT peak standardized uptake value for chronic osteomyelitis, osteoradionecrosis and medication-related osteonecrosis of the jaw. J Med Imaging Radiat Oncol. 2021;65(2):160-165.
Kim J, Lee H, Lee H, et al. Quantitative single-photon emission computed tomography/computed tomography for evaluation of salivary gland dysfunction in Sjögren’s syndrome patients. Nucl Med Mol Imaging. 2018;52:368-376.
Ninomiya K, Toya S, Ogura I. Single-photon emission computed tomography/computed tomography for evaluation of salivary gland dysfunction: preliminary study on diagnostic ability of maximum standardised uptake value. Oral Radiol. 2020;36:163-167.